Patient Information Leaflet

Ibuprofen Hasco
200 mg, soft capsules
Ibuprofenum
Please read this leaflet carefully before using the medicine, as it contains
important information for the patient.

Keep this leaflet for future reference.
If you have any questions, please consult your doctor or pharmacist.
This medicine has been prescribed for a specific individual. Do not give it to others. The medicine may harm another person, even if their symptoms are the same.
If you experience any adverse effects, including any not listed in this leaflet, inform your doctor or pharmacist. See section 4.

Table of Contents

What is Ibuprofen Hasco and what is it used for
Important information before taking Ibuprofen Hasco
How to take Ibuprofen Hasco
Possible side effects
How to store Ibuprofen Hasco
Contents of the pack and other information

1. What is Ibuprofen Hasco and what is it used for

Ibuprofen Hasco contains ibuprofen – an active substance belonging to the group of non-steroidal anti-inflammatory drugs (NSAIDs), which have analgesic, antipyretic, and anti-inflammatory properties.
The indications for use are:

mild to moderate pain of various origins (headaches, including migraines, toothaches, muscle, joint and bone pain, pain following injuries, neuralgias, pain associated with colds and flu),
painful menstruation,
fever of various causes (e.g. associated with influenza, colds or other infectious diseases),
symptomatic treatment of osteoarthritis and rheumatoid arthritis (including juvenile rheumatoid arthritis).

2. Important information before using Ibuprofen Hasco

When not to use Ibuprofen Hasco

if the patient is allergic to ibuprofen or any of the other ingredients of this medicine (listed in section 6),
in patients who have previously experienced any allergic symptoms such as rhinitis, urticaria or bronchial asthma during treatment with acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs),
in patients who have previously experienced gastrointestinal perforation (gut perforation) or bleeding related to prior NSAID therapy,
if there is active or recurrent peptic ulceration of the stomach and/or duodenum, or gastrointestinal bleeding (previous serious bleeding or more than one episode of ulcers or bleeding),
if there is severe liver or kidney failure,
if there is severe heart failure or coronary artery disease,
in patients with haemorrhagic diathesis (tendency to bleed),
during the last three months of pregnancy,
if there is cerebral haemorrhage or other active bleeding,
in children under 6 years of age weighing less than 20 kg,
if the patient is significantly dehydrated (due to vomiting, diarrhoea or insufficient fluid intake),
if the patient has an unknown origin disease leading to the formation of abnormal blood cells.

Warnings and precautions
Before starting to use Ibuprofen Hasco, discuss this with your doctor or pharmacist.
Exercise particular caution when using Ibuprofen Hasco:

in patients diagnosed with autoimmune diseases (systemic lupus erythematosus, connective tissue disorders), due to increased risk of aseptic meningitis symptoms,
in patients diagnosed with inherited porphyria metabolism disorders (e.g. acute intermittent porphyria),
in patients diagnosed with gastrointestinal diseases and chronic inflammatory bowel diseases (ulcerative colitis, Crohn's disease),
in patients diagnosed with hypertension and/or heart function disorders,
in patients diagnosed with impaired kidney or liver function,
in patients diagnosed with fluid retention and oedema associated with taking NSAIDs,
in patients taking anticoagulant drugs, or in patients diagnosed with blood clotting disorders (ibuprofen may temporarily inhibit platelet aggregation and prolong bleeding time),
in patients with blood cell formation disorders,
in patients with active or previous asthma or allergic reaction symptoms (bronchospasm may occur after administration of the drug),
immediately after major surgical procedures,
in patients taking other medicines (especially anticoagulants, diuretics, cardiac drugs or corticosteroids),
when administering the drug to elderly patients (see section 3).

Avoid concomitant use of Ibuprofen Hasco with other non-steroidal anti-inflammatory drugs, including selective cyclooxygenase-2 inhibitors, as this increases the risk of adverse effects.
Patients with a history of gastrointestinal disorders, particularly elderly patients, should report any unusual gastrointestinal symptoms (especially bleeding) to their doctor, especially during the initial treatment period.
Exercise particular caution and consult your doctor or pharmacist before using the medicine in patients with hypertension and/or heart failure with fluid retention, hypertension and oedema previously associated with NSAID use.
Taking anti-inflammatory/pain-relieving medicines such as ibuprofen may be associated with a small increased risk of heart attack or stroke, especially when used at high doses. Do not exceed the recommended dose or duration of treatment.
Before using Ibuprofen Hasco, the patient should discuss treatment with a doctor or pharmacist if:

the patient has heart diseases such as heart failure, angina pectoris (chest pain), has had a heart attack, coronary artery bypass surgery, peripheral arterial disease (poor blood circulation in the legs due to narrowed or blocked arteries), or has had any stroke (including mini-stroke or transient ischaemic attack - TIA),
the patient has hypertension, diabetes, elevated cholesterol levels, a family history of heart disease or stroke, or if the patient smokes,
the patient has an infection – see below, section titled "Infections".

Symptoms of allergic reaction to ibuprofen, including difficulty breathing, facial and neck swelling (angioedema), chest pain, have been reported.
If any of these symptoms occur, discontinue Ibuprofen Hasco immediately and contact a doctor or emergency medical services without delay.
There is a risk of gastrointestinal haemorrhage, ulceration or perforation, which may be fatal and may occur without warning symptoms or in patients with previous warning symptoms. If gastrointestinal bleeding or ulceration occurs, discontinue ibuprofen. Patients with a history of gastrointestinal disorders, particularly elderly patients, should report any unusual gastrointestinal symptoms (especially bleeding) to their doctor, especially during the initial treatment period. These patients should use the lowest effective dose of the medicine.
Exercise caution when using ibuprofen in patients concurrently taking other medicines that may increase the risk of gastric and intestinal disorders or bleeding, such as corticosteroids or anticoagulants (e.g. acenocoumarol or heparin), selective serotonin reuptake inhibitors or antiplatelet agents such as acetylsalicylic acid.
Ibuprofen may cause sodium, potassium and fluid retention in patients who have not previously had kidney disease. This may in turn cause oedema or even lead to heart failure or hypertension in patients predisposed to such disorders.
Long-term use of ibuprofen, especially in combination with other painkillers, may cause permanent kidney damage and risk of kidney failure.
Patients at highest risk of such reactions are those with impaired kidney function, heart failure, impaired liver function, those taking diuretics and antihypertensives (ACE inhibitors), and elderly patients. Patients who discontinue treatment with NSAIDs generally return to their pre-treatment state.

Skin reactions
Severe skin reactions associated with the use of Ibuprofen Hasco have been reported. If any skin rash, mucosal changes, blisters or other allergic symptoms appear, discontinue taking Ibuprofen Hasco and seek immediate medical help, as these may be the first signs of a very serious skin reaction. See section 4.
Serious skin reactions such as exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalised exanthematous pustulosis (AGEP) have occurred with ibuprofen use. If the patient develops any symptoms related to these serious skin reactions described in section 4, Ibuprofen Hasco should be discontinued immediately and medical help sought.
During long-term ibuprofen treatment, periodic monitoring of liver and kidney function and blood cell counts is necessary, especially in high-risk patients.

Infections
Ibuprofen Hasco may mask infection symptoms such as fever and pain. Therefore, Ibuprofen Hasco may delay appropriate infection treatment and consequently increase the risk of complications. This has been observed in bacterial pneumonia and bacterial skin infections associated with chickenpox. If the patient takes this medicine during an existing infection and infection symptoms persist or worsen, immediate consultation with a doctor is required.

During long-term treatment with high doses of painkillers, headaches may occur, which should not be treated with increased doses of medication.
Ibuprofen may temporarily inhibit platelet aggregation and prolong bleeding time. Therefore, patients with clotting disorders or undergoing anticoagulant therapy should be carefully monitored.
Avoid alcohol consumption during treatment with this medicine, as it may increase adverse effects, particularly those related to the gastrointestinal tract and nervous system.

Effect on fertility in women
See section "Pregnancy, breastfeeding and effect on fertility".

Children and adolescents
In dehydrated patients – children and adolescents – there is a risk of impaired kidney function.

Elderly patients
In elderly patients, there is an increased risk of adverse effects caused by NSAID use, especially gastrointestinal bleeding and perforation, which may be fatal (see section 3).
Using the medicine at the lowest effective dose for the shortest duration necessary to relieve symptoms reduces the risk of adverse effects.

Ibuprofen Hasco and other medicines
Inform your doctor or pharmacist about all medicines currently or recently taken, and any medicines planned for use.
Avoid taking Ibuprofen Hasco when using other NSAIDs (including cyclooxygenase-2 inhibitors such as celecoxib or etoricoxib), other painkillers or acetylsalicylic acid (at analgesic doses).
Ibuprofen Hasco may affect the action of other medicines or other medicines may affect the action of Ibuprofen Hasco. For example:

anticoagulant drugs (i.e. blood thinners/preventing clot formation, such as aspirin/acetylsalicylic acid, warfarin, ticlopidine);
blood pressure-lowering drugs (ACE inhibitors, such as captopril, beta-blockers such as atenolol-containing drugs, angiotensin II receptor antagonists such as losartan).

Some other medicines may also be affected by or affect the treatment with Ibuprofen Hasco.
Therefore, always consult a doctor or pharmacist before taking Ibuprofen Hasco with other medicines.
In particular, inform your doctor before taking ibuprofen if you are taking any of the following medicines:

low-dose acetylsalicylic acid (75 mg) once daily,
antihypertensive drugs (including ACE inhibitors),
beta-blockers (β-blockers),
diuretics and potassium-sparing drugs,
methotrexate (an anticancer drug),
drugs reducing blood coagulation (anticoagulants, e.g. acenocoumarol or antiplatelet drugs, e.g. clopidogrel and ticlopidine),
moclobemide and lithium (antidepressants),
serotonin reuptake inhibitors (antidepressants),
cardiac glycosides (e.g. digoxin),
phenytoin (an antiepileptic drug),
corticosteroids (e.g. prednisolone or dexamethasone),
cyclosporine and tacrolimus (immunosuppressants),
zidovudine and ritonavir (antiviral drugs),
antibiotics (quinolones or aminoglycosides),
sulfonylurea derivatives (antidiabetic drugs),
probenecid and sulfinpyrazone (drugs used, among others, in gout treatment).

Some anticoagulants (e.g. acetylsalicylic acid, acenocoumarol, warfarin, ticlopidine), some antihypertensive drugs (ACE inhibitors, e.g. captopril, beta-receptor blockers, angiotensin II antagonists) and some other drugs may be affected by or affect ibuprofen action. Therefore, always seek medical advice before taking ibuprofen concomitantly with other drugs.

Pregnancy, breastfeeding and effect on fertility
If the patient is pregnant or breastfeeding, suspects she may be pregnant, or is planning to have a child, she should consult her doctor or pharmacist before using this medicine.

Pregnancy
Do not take Ibuprofen Hasco if you are in the last three months of pregnancy, as it may harm the unborn child or cause complications during delivery. It may cause kidney and heart problems in the unborn child. It may increase the tendency to bleeding in both mother and child and may delay or prolong labour. Do not use the medicine during the first 6 months of pregnancy unless absolutely necessary and prescribed by a doctor. If treatment is necessary during this period or when trying to conceive, use the lowest possible dose for the shortest possible time. From the 20th week of pregnancy, Ibuprofen Hasco may cause kidney function disorders in the unborn child; if taken for longer than a few days, it may lead to reduced amniotic fluid volume (oligohydramnios) or narrowing of the blood vessel (ductus arteriosus) in the child's heart. If treatment is required for longer than a few days, your doctor may recommend additional monitoring.

Breastfeeding
Ibuprofen passes into breast milk in small amounts. With short-term use of ibuprofen at doses used for pain and fever treatment, harmful effects on infants seem unlikely. However, if prolonged ibuprofen use is recommended, consider earlier weaning.

Fertility
Ibuprofen may impair fertility. If the patient plans to become pregnant or has difficulty conceiving, she should inform her doctor.

Driving and operating machinery
Ibuprofen Hasco generally does not affect the ability to drive or operate machinery. However, adverse effects associated with high doses of the drug, such as fatigue, drowsiness, dizziness (frequently reported) and visual disturbances (reported less frequently), may in individual cases impair the ability to drive and operate machinery. This effect may be intensified by concomitant alcohol consumption.

Ibuprofen Hasco contains sorbitol and sodium
The medicine contains 62.5 mg of sorbitol per capsule. Sorbitol is a source of fructose. If the patient has previously been diagnosed with intolerance to certain sugars or hereditary fructose intolerance, a rare genetic disorder in which the patient's body does not break down fructose, the patient should consult a doctor before taking the medicine or giving it to a child.
Quinoline yellow (E 104) and patent blue (E 131) in the capsule shell contain sodium. The medicine contains less than 1 mmol (23 mg) of sodium per capsule, meaning the medicine is considered "sodium-free".

3. How to use Ibuprofen Hasco

This medicine should always be used according to the instructions given by your doctor or pharmacist. If you have any doubts,
you should consult your doctor or pharmacist.
This medicine is for oral use.
Ibuprofen Hasco should always be used according to your doctor's instructions. The dose of ibuprofen depends on
the patient's age and body weight.
The lowest effective dose should be used for the shortest duration necessary to relieve symptoms. If, during an infection, its symptoms (such as fever and pain) persist or
worsen, you should consult your doctor immediately (see section 2).
This medicine is intended for patients weighing more than 20 kilograms (approximately 6 years of age).

Mild to moderate pain and fever
Adults and adolescents over 12 years of age (body weight ≥ 40 kg):
Initial dose: 1 to 2 capsules (200 mg – 400 mg ibuprofen).
Then, if needed, 1 (200 mg) to 2 (400 mg) capsules every 4 hours (for 200 mg dose) to 6 hours (for
400 mg dose). The maximum daily dose should not exceed 1200 mg (6 capsules).
Dosing for migraine pain: 400 mg (2 capsules) as a single dose; if necessary, 400 mg repeated every 4 to 6 hours. The maximum daily dose should not
exceed 1200 mg (6 capsules).

Children aged 6–12 years (body weight > 20 kg):
Children aged 6–9 years (20–29 kg): the usual daily dose is 20 mg/kg body weight, divided into doses. Initial dose: 200 mg (1 capsule). Then, if needed, 1 capsule every 8
hours. The maximum daily dose is 3 capsules (600 mg ibuprofen).
Children aged 10–12 years (body weight 30–39 kg): initial dose 200 mg (1 capsule). Then, if needed, 1 capsule every 6 hours. The maximum daily dose is 4 capsules (800 mg
ibuprofen).

Painful menstruation
Adults and adolescents over 12 years of age:
200–400 mg (1–2 capsules), 1–3 times daily as needed, with intervals of 4 to 6 hours.
The maximum daily dose should not exceed 1200 mg (6 capsules).

Symptomatic treatment of osteoarthritis and rheumatoid arthritis (including juvenile rheumatoid arthritis):
Adults and adolescents over 12 years of age:
The usual dose is 400–600 mg (2–3 capsules) three times daily. A maintenance dose of 600–
1200 mg (3–6 capsules) may be effective in some patients. In acute and severe conditions, the dose may be increased up to a maximum of 2400 mg (12 capsules) divided into 3 or 4 doses.
After clinical improvement is achieved, the dose should be reduced to the lowest effective dose.

Children aged 6–12 years with juvenile rheumatoid arthritis:
The recommended dose is 20 mg/kg to 40 mg/kg body weight per day, divided into 3 or 4 doses.
After improvement is achieved, the dose should be reduced to the lowest effective dose.

Elderly patients:
Non-steroidal anti-inflammatory drugs (NSAIDs) should be used with caution, especially in elderly patients who are more susceptible to the risk of adverse effects and potentially fatal gastrointestinal bleeding, ulcers, and perforations.
If treatment is necessary, Ibuprofen Hasco should be used at the lowest possible dose for the shortest duration needed to control symptoms. Treatment should be regularly reviewed and discontinued if no benefit is observed or if signs of intolerance occur.

Renal function disorders:
In patients with mild to moderate renal impairment, the dose should be as low as possible and used for the shortest possible duration necessary to control symptoms, with regular monitoring of kidney function.

Hepatic function disorders:
In patients with mild to moderate hepatic impairment, the dose should be as low as possible and used for the shortest possible duration necessary to control symptoms, with regular monitoring of liver function.

If symptoms worsen despite treatment, you should contact your doctor.

Taking more than the recommended dose of Ibuprofen Hasco
If a patient takes more than the recommended dose of Ibuprofen Hasco or if a child accidentally takes the medicine, you should always consult a doctor or go to the nearest hospital to assess possible health risks and receive advice on what actions to take.
Symptoms may include nausea, stomach pain (epigastric pain), less commonly diarrhoea, vomiting (possibly with blood), headache, ringing in the ears (tinnitus), confusion and nystagmus. After a large dose, drowsiness, chest pain, palpitations, loss of consciousness, seizures (mainly in children), weakness and dizziness, blood in urine, cold sensation, breathing difficulties, and gastrointestinal bleeding may occur.
Cases of overdose are rare.
In children, a single dose exceeding 400 mg (2 capsules) may cause symptoms of overdose. In adults, the dose that may cause such symptoms has not been precisely established.
Severe poisoning may cause central nervous system disturbances manifesting as drowsiness, very rarely excitement and confusion, or coma. Seizures may very rarely occur. In children, myoclonic jerks (repetitive muscle spasms) may occur.
During severe poisoning, metabolic acidosis (acid-base imbalance) may occur, and the prothrombin time (a coagulation parameter) may be prolonged.
Acute renal failure, liver damage, hypotension, respiratory depression, or cyanosis may occur.
In patients with asthma, worsening of asthma symptoms may occur.
There is no specific antidote. Symptomatic and supportive treatment should be administered, including decontamination of the body. The doctor should monitor vital signs and consider administering activated charcoal orally within 1 hour of overdose.
If symptoms of overdose occur, the medicine should be discontinued immediately and medical advice sought.

Missed dose of Ibuprofen Hasco
Do not take a double dose to make up for a missed dose.
If you have any further doubts about using this medicine, consult your doctor.

4. Possible adverse effects

Like all medicines, this medicine can cause adverse effects, although not everyone experiences them.
The list below includes all adverse effects observed during treatment with ibuprofen, including those occurring after long-term therapy with high doses used in patients with rheumatic disease.
With regard to the adverse reactions listed below, it should be remembered that they are predominantly dose-dependent and their occurrence varies individually.
Patients taking Ibuprofen Hasco should discontinue the medicine and immediately consult a doctor if symptoms or signs of ulceration, mucosal damage, or gastrointestinal bleeding occur (tarry stools, vomiting blood), acute upper abdominal pain, blurred vision or other eye-related symptoms, skin rash or other hypersensitivity reactions, weight gain or swelling.
If any of the following symptoms occur in a patient, ibuprofen use must be stopped immediately and medical help sought:

Red, flat, non-elevated, target-like or circular spots on the trunk, often with blisters in the center, skin peeling, and ulceration in the mouth, throat, nose, genital organs, and eyes. These severe skin rashes may be preceded by fever and flu-like symptoms (exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis),
Widespread rash, high fever, and enlarged lymph nodes (DRESS syndrome),
Red, scaly rash with subcutaneous nodules and blisters, accompanied by fever. Symptoms usually appear at the beginning of treatment (acute generalized exanthematous pustulosis).

The most commonly observed adverse reactions involve the gastrointestinal tract. Ulceration, perforation, or gastrointestinal bleeding may occur, sometimes with fatal outcome (particularly in elderly patients). These may occur without preceding warning symptoms or may occur in patients who previously experienced such warning signs.
The risk of gastrointestinal bleeding is particularly dependent on the dose range and duration of ibuprofen use.
Taking ibuprofen, especially long-term at high doses (2400 mg per day), may be associated with a small increased risk of arterial thrombosis (e.g., myocardial infarction or stroke).
Other possible adverse effects include:
Common (occur in 1 to 10 out of 100 patients):

Heartburn, abdominal pain, nausea, vomiting, bloating with gas, diarrhea, indigestion, constipation, and minor gastrointestinal bleeding, which may exceptionally lead to anemia.

Uncommon (occur in 1 to 10 out of 1,000 patients):

Hypersensitivity reactions with skin rash and itching, as well as asthma attacks (possibly occurring together with a drop in blood pressure). In such cases, the medicine should be discontinued and medical advice sought immediately,
Headache, drowsiness, dizziness, insomnia, restlessness, irritability, or fatigue,
Visual disturbances,
Gastrointestinal ulcers, potentially with bleeding and perforation, oral mucosal ulcers, exacerbation of ulcerative colitis, Crohn's disease, gastric mucositis, tarry stools, vomiting blood.

Rare (occur in 1 to 10 out of 10,000 patients):

Tinnitus,
Kidney tissue damage (papillary necrosis) and increased blood uric acid levels.

Very rare (occur in fewer than 1 out of 10,000 patients):

Severe, generalized hypersensitivity reactions. These may present as facial swelling, tongue swelling, internal laryngeal swelling with impaired airway patency, respiratory insufficiency, rapid heartbeat, low blood pressure, up to life-threatening shock. If any of the above symptoms occur, which may happen even after the first dose of the medicine, immediate medical assistance is required,
Bullous reactions, including Stevens-Johnson syndrome (a severe, life-threatening type of allergic reaction), toxic epidermal necrolysis, and exfoliative dermatitis. The highest risk of these severe reactions occurs at the beginning of therapy, in most cases within the first month of treatment,
Blood-forming system disorders (anemia, leukopenia, thrombocytopenia, pancytopenia, agranulocytosis). Initial symptoms may include fever, sore throat, oral ulcers, flu-like symptoms, marked weakness, nosebleeds, and subcutaneous hemorrhages. During long-term use of the medicine, blood morphology parameters should be monitored regularly,
Development of edema, particularly with hypertension or renal failure, nephrotic syndrome, interstitial nephritis associated with acute renal failure. For this reason, kidney function should be monitored regularly during prolonged treatment,
Liver function disorders, liver damage (especially with long-term use), liver failure, acute hepatitis. Therefore, liver function should be monitored regularly during prolonged treatment,
Palpitations, heart failure, myocardial infarction,
Hypertension,
Esophagitis, pancreatitis, development of diaphragm-like intestinal strictures,
Psychotic reactions, depression,
Infections associated with conditions for which non-steroidal anti-inflammatory drugs are used (e.g., necrotizing fasciitis). If signs or symptoms of infection appear or worsen during ibuprofen use, the patient should seek immediate medical advice. The doctor will assess whether antimicrobial treatment (antibiotic therapy) is indicated. During ibuprofen use, symptoms of aseptic meningitis have been observed, including neck stiffness, headache, nausea, vomiting, fever, or disturbances in consciousness,
In exceptional cases, during varicella virus infection, severe skin infections and soft tissue complications may occur.

Frequency unknown (frequency cannot be estimated from available data):

Chest pain, which may be a symptom of a potentially serious allergic reaction known as Kounis syndrome.
Severe skin reactions known as DRESS syndrome. Symptoms of DRESS syndrome include: skin rash, fever, lymph node swelling, and increased eosinophil count (a type of white blood cell).
Red, scaly rash with subcutaneous nodules and blisters, predominantly located in skin folds, trunk, and upper limbs, with fever occurring at the beginning of treatment (acute generalized exanthematous pustulosis). If such symptoms occur, Ibuprofen Hasco should be discontinued immediately and medical help sought without delay. See also section 2,
Skin becomes sensitive to light.

Reporting of adverse effects
If any adverse effects occur, including any not listed in this leaflet, inform your doctor, pharmacist, or nurse. Adverse effects can be reported directly to the Department of Monitoring Adverse Drug Reactions, Office for Registration of Medicinal Products, Medical Devices and Biocidal Products:
Al. Jerozolimskie 181C, 02-222 Warsaw
Tel.: +48 22 49 21 301, Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Adverse effects can also be reported to the responsible entity.
Reporting adverse effects helps gather more information on the safety of medicine use.

5. How to store Ibuprofen Hasco

Store below 25°C. Keep in the original packaging to protect from moisture.
Keep the medicine out of sight and reach of children.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the stated month.
Medicines must not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. Such measures help protect the environment.

6. Contents of the pack and other information

What Ibuprofen Hasco contains

The active substance is ibuprofen. Each soft capsule contains 200 mg of ibuprofen.
The other ingredients (excipients) are: macrogol 400, potassium hydroxide 50%, gelatin, partially dehydrated liquid sorbitol, quinoline yellow (E 104), patent blue (E 131).

What Ibuprofen Hasco looks like and contents of the pack
Ibuprofen Hasco is in the form of oval, green, transparent soft capsules filled with liquid ibuprofen, with a smooth and glossy surface.
The pack contains 60 soft capsules.
Marketing Authorisation Holder and Manufacturer
"PRZEDSIĘBIORSTWO PRODUKCJI FARMACEUTYCZNEJ HASCO-LEK" S.A.
51-131 Wrocław, ul. Żmigrodzka 242 E
Medicinal product information
tel.: 22 742 00 22
e-mail: [email protected]

Ibuprofen hasco