Ketoprofen lysine salt Zentiva Italia: detailed information

Package leaflet: Information for the patient

Ketoprofene sale di lisina Zentiva Italia 40 mg granulate

Ketoprofene Lysine Salt
Read this leaflet carefully before taking this medicine because it contains
important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor or
pharmacist has instructed you.

Keep this leaflet. You may need to read it again.
If you need more information or advice, consult your pharmacist.
If you experience any side effects, including those not listed in this leaflet, contact your doctor or pharmacist. See section 4.
Contact your doctor if you do not notice improvement or if you notice worsening of symptoms after short periods of treatment.

Contents of this leaflet:

What Ketoprofene sale di lisina Zentiva Italia is and what it is used for
What you need to know before taking Ketoprofene sale di lisina Zentiva Italia
How to take Ketoprofene sale di lisina Zentiva Italia
Possible side effects
How to store Ketoprofene sale di lisina Zentiva Italia
Contents of the pack and other information

1. What Ketoprofene sale di lisina Zentiva Italia is and what it is used for

Ketoprofene sale di lisina Zentiva Italia contains the active substance ketoprofene, which belongs to a group of medicines called non-steroidal anti-inflammatory drugs ("NSAIDs"), used to treat pain and inflammation.
Ketoprofene sale di lisina Zentiva Italia is indicated in adults and adolescents over 15 years of age for the treatment of mild to moderate acute pain.

2. What you need to know before taking Ketoprofene lysine salt Zentiva Italia

Do not take Ketoprofene lysine salt Zentiva Italia

if you are allergic to ketoprofen, to other non-steroidal anti-inflammatory drugs (NSAIDs), or to any of the other ingredients of this medicine (listed in section 6);
if taking ketoprofen or medicines with a similar mechanism of action, such as acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs), has previously caused you hypersensitivity reactions (allergy) such as asthma (bronchial inflammation and narrowing of the airways), bronchospasm (breathing difficulties due to temporary narrowing of the bronchi), allergic rhinitis (allergic inflammation of the nasal mucosa), urticaria, skin rashes, nasal polyps, angioedema (swelling of the skin and mucous membranes), or other allergic-type reactions;
allergic skin reactions such as urticaria or swelling of the face, lips, mouth, tongue, or throat, which may cause difficulty in swallowing and breathing (angioedema). In such cases, a sudden allergic reaction may occur, which can be life-threatening;
if you suffer from bronchial asthma (bronchial inflammation and narrowing of the airways);
if you have severe heart failure (inability of the heart to pump sufficient blood to meet the body's needs);
if you have gastritis (inflammation of the stomach lining);
if you currently have a peptic ulcer (a lesion in the stomach or the first part of the intestine) or gastrointestinal bleeding, or if you have previously experienced recurrent peptic ulcer or bleeding (two or more distinct, confirmed episodes of bleeding or ulceration);
if you have previously suffered from gastrointestinal bleeding (bleeding of the stomach or intestine), ulceration, perforation, or chronic dyspepsia (indigestion);
if you currently suffer or have previously suffered from bleeding or perforation of the stomach or intestine, even after taking non-steroidal anti-inflammatory drugs (NSAIDs);
if you suffer from Crohn’s disease (inflammation of the intestine) or ulcerative colitis (inflammation of the intestine with ulcers);
if you have severe liver failure (reduced liver function due to cirrhosis or severe hepatitis) or kidney failure (reduced kidney function);
if you have leukopenia (reduced number of white blood cells) or thrombocytopenia (reduced number of platelets);
if you have a predisposition to bleeding (hemorrhagic diathesis) or a blood coagulation disorder, or if you have hemostatic disorders (difficulty in stopping bleeding); or if you are taking medications to improve blood fluidity (anticoagulants);
if you are undergoing treatment with high-dose diuretics;
if you are in the last three months of pregnancy or breastfeeding (see section “Pregnancy, breastfeeding and fertility”);
if the person to take the medicine is a child or adolescent under 15 years of age.

Warnings and precautions
Talk to your doctor or pharmacist before taking Ketoprofene lysine salt Zentiva Italia.
Warnings
Undesirable effects can be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms (see “How to take Ketoprofene lysine salt Zentiva Italia” and the sections below on gastrointestinal and cardiovascular risks).
Concomitant use of Ketoprofene lysine salt Zentiva Italia with other anti-inflammatory drugs should be avoided.
During treatment with all NSAIDs, including Ketoprofene lysine salt Zentiva Italia, gastrointestinal bleeding, ulceration, and perforation—potentially fatal—have been reported at any time, with or without warning symptoms or previous history of serious gastrointestinal events. Patients with a prior history of these conditions are at higher risk (see “Do not take Ketoprofene lysine salt Zentiva Italia”).
Report any abdominal signs or symptoms (including gastrointestinal bleeding) even at the beginning of treatment.
Inform your doctor if you are taking medications that may increase the risk of peptic ulcer or bleeding, such as oral corticosteroids (medicines used to treat inflammatory conditions), anticoagulant agents that delay blood clot formation (e.g., warfarin), certain antidepressants (selective serotonin reuptake inhibitors), or antiplatelet agents (medicines that prevent platelet aggregation) such as acetylsalicylic acid (see section “Other medicines and Ketoprofene lysine salt Zentiva Italia”). In such cases, consult your doctor before taking Ketoprofene lysine salt Zentiva Italia, as you may need to take an additional medicine to protect your stomach (e.g., misoprostol or medicines that block stomach acid production).
Elderly patients are at increased risk of developing adverse reactions to NSAIDs, particularly stomach or intestinal lesions or bleeding, which may be life-threatening.
Immediately discontinue treatment with Ketoprofene lysine salt Zentiva Italia at the first signs of gastrointestinal bleeding or ulceration.
Severe skin reactions, some of which have been fatal, such as exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been very rarely reported in association with NSAID use (see “Possible side effects”). These reactions usually occur during the initial stages of treatment. Discontinue use of Ketoprofene lysine salt Zentiva Italia if a skin rash, mucosal lesions, or any other sign of hypersensitivity (allergic reaction) appears.

Precautions
Consult your doctor or pharmacist before taking Ketoprofene lysine salt Zentiva Italia:

If your kidneys do not function properly, as Ketoprofene lysine salt Zentiva Italia should be used with caution in such cases. If you use Ketoprofene lysine salt Zentiva Italia, kidney function should be monitored, especially if you are elderly or taking diuretics (medicines that lower blood pressure).
If you have liver problems, periodic monitoring is required.
If you have an infection – see the section «Infections» below.
If you have uncontrolled hypertension (high blood pressure), congestive heart failure (fluid accumulation in the lungs, abdominal organs, and peripheral tissues due to inadequate cardiac pumping function), established ischemic heart disease (heart condition due to reduced blood flow caused by narrowing of the coronary arteries), peripheral arterial disease, and/or cerebrovascular disease (disease of the brain arteries and vessels), as Ketoprofene lysine salt Zentiva Italia should only be taken after careful evaluation by your doctor.
If you have risk factors for these conditions, such as high blood pressure, diabetes (a disease caused by high blood glucose levels), hyperlipidemia (high blood fat levels), or if you smoke.
If you have experienced allergic reactions or have a history of allergies, as the medicine should be administered with caution.
If you suffer from bronchial asthma (bronchial inflammation and narrowing of the airways) or allergic diathesis (predisposition to develop allergies), chronic rhinitis (inflammation of the nasal mucosa), allergic rhinitis, chronic sinusitis, and/or nasal polyposis.
If you have hematopoietic disorders (affecting blood cell formation and maturation), systemic lupus erythematosus (an immune system disease), or mixed connective tissue disease (immune system disorders affecting connective tissue).
If you have hepatic porphyria (a rare blood disorder characterized by impaired activity of a liver enzyme), as the medicine could trigger an attack.
If you are taking other non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, even at low doses (see section “Other medicines and Ketoprofene lysine salt Zentiva Italia”).
If you currently suffer or have previously suffered from stomach and/or intestinal problems (e.g., peptic ulcers, perforation, or gastrointestinal bleeding). In such cases, your doctor may decide to monitor you closely and prescribe an additional medicine to protect your stomach (e.g., misoprostol or acid-suppressing medicines).
If you have previously suffered from chronic inflammatory bowel disease (ulcerative colitis, Crohn’s disease).
If you are a woman with fertility problems and planning a pregnancy, as this medicine may interfere with fertility.

Some NSAIDs may be associated with an increased risk of arterial thrombotic events (e.g., heart attack or stroke). Currently, there are insufficient data to exclude a similar risk for Ketoprofene lysine salt Zentiva Italia.
An increased risk of atrial fibrillation (abnormal heart rhythm) has been reported with the use of NSAIDs.
Hyperkalemia (increased blood potassium levels) may occur, particularly if you have diabetes, kidney failure, and/or are taking medicines that may cause hyperkalemia (see “Other medicines and Ketoprofene lysine salt Zentiva Italia”). In such cases, potassium levels should be monitored periodically.
Ketoprofene lysine salt Zentiva Italia may mask symptoms of infections such as fever and pain. Therefore, it may delay appropriate treatment of the infection, increasing the risk of complications. This has been observed in bacterial pneumonia and bacterial skin infections related to varicella. If you take this medicine while having an infection and infection symptoms persist or worsen, consult your doctor immediately.
Consult your doctor if you experience visual disturbances, such as blurred vision, as treatment must be discontinued.
Avoid sun exposure during treatment with this medicine, as the skin may become more sensitive.

Children and adolescents
Ketoprofene lysine salt Zentiva Italia must not be administered to children and adolescents under 15 years of age.

Other medicines and Ketoprofene lysine salt Zentiva Italia
Inform your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine.

Concomitant use of Ketoprofene lysine salt Zentiva Italia is not recommended with: other non-steroidal anti-inflammatory drugs (NSAIDs), selective cyclooxygenase-2 inhibitors, and high-dose salicylates (more than 3 g per day);
medicines used to slow blood clotting (anticoagulants such as heparin and warfarin) and medicines that prevent platelet aggregation (antiplatelet agents such as ticlopidine and clopidogrel);
lithium, used to treat manic-depressive psychosis;
high-dose methotrexate (more than 15 mg per week), used to treat certain autoimmune diseases and some cancers;
hydantoins, used for epilepsy; sulfonamides, such as certain antibiotics used for bacterial infections.

Caution is required when using Ketoprofene lysine salt Zentiva Italia concomitantly with:

Potassium salts;
Potassium-sparing diuretics, ACE inhibitors, angiotensin receptor antagonists II, used for high blood pressure or heart problems;
NSAIDs, anti-inflammatory drugs;
Heparins, anticoagulants;
Cyclosporine and tacrolimus, used to prevent organ transplant rejection or for certain immune system diseases;
Trimethoprim, an antibiotic used for bacterial infections;
Tenofovir, used in the treatment of certain viral infections;
Methotrexate at doses below 15 mg/week, indicated for the treatment of certain autoimmune diseases and some cancers;
Corticosteroids, used to treat inflammatory conditions;
Pentoxifylline, used to improve blood circulation in the limbs;
Zidovudine, used for HIV treatment;
Sulfonylureas, used to treat diabetes;
Cardiac glycosides, medicines acting on the heart.
Consider the combination of Okitask with: beta-blockers, ACE inhibitors, diuretics, used to lower blood pressure;
Mifepristone, used for medical termination of pregnancy;
Intrauterine contraceptive devices;
Thrombolytics, used to facilitate the dissolution of blood clots;
Probenecid, used for gout;
Certain antidepressants, known as selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants;
Cyclosporine and tacrolimus, used after organ transplantation or for the treatment of immune system disorders;
Certain antibiotics, used against bacterial infections.

Your doctor should monitor you and may decide to reduce the dose of Ketoprofene lysine salt Zentiva Italia.

Pregnancy, breastfeeding and fertility
If you are pregnant, suspect you may be pregnant, planning a pregnancy, or breastfeeding, consult your doctor or pharmacist before taking this medicine.

Pregnancy
Ketoprofen use during the first and second trimesters of pregnancy should be avoided. Ketoprofen should only be considered if the expected benefit to the mother outweighs the risk to the embryo or fetus. Do not use Okitask during the first and second trimesters of pregnancy unless strictly necessary and under medical advice. If treatment is required during this period or during attempts to conceive, the lowest possible dose for the shortest possible duration should be used.
During the last three months of pregnancy, all medicines in the class of Ketoprofene lysine salt Zentiva Italia may expose the fetus to:

Cardiopulmonary toxicity;
Renal dysfunction;

and the mother and newborn at the end of pregnancy to:

Possible prolongation of bleeding time and anti-aggregating effects, which may occur even at very low doses;
Inhibition of uterine contractions, leading to delayed or prolonged labor.

Use of the medicine close to delivery may cause disturbances in the newborn’s circulation and respiration. Therefore, DO NOT take Ketoprofene lysine salt Zentiva Italia during the third trimester of pregnancy (see “Do not take Ketoprofene lysine salt Zentiva Italia”).
From week 20 of pregnancy, Ketoprofene lysine salt Zentiva Italia may cause fetal kidney problems if taken for more than a few days, reducing amniotic fluid levels surrounding the baby (oligohydramnios) or causing narrowing of a blood vessel (ductus arteriosus) in the baby’s heart. If treatment is required for more than a few days, your doctor may recommend additional monitoring.

Breastfeeding
There is no available information on the excretion of ketoprofen in human breast milk.
Ketoprofene lysine salt Zentiva Italia is not recommended during breastfeeding.

Fertility
The use of NSAIDs, including Ketoprofene lysine salt Zentiva Italia, may cause fertility problems in women. Therefore, it is not recommended if you are planning to become pregnant.
Discontinue treatment if you have fertility issues and are planning a pregnancy, or if you are undergoing fertility testing.

Driving and using machines
This medicine may cause dizziness, drowsiness, seizures, and visual disturbances. If you experience any of these, it is recommended to avoid driving, operating machinery, or performing activities requiring special alertness (see “Possible side effects”).

Ketoprofene lysine salt Zentiva Italia contains aspartame
This medicine contains 10.56 mg of aspartame per dose (1 sachet), equivalent to 31.78 mg per maximum recommended daily dose (3 sachets).
Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria, a rare genetic disorder causing phenylalanine accumulation due to the body’s inability to properly metabolize it.

3. How to take Ketoprofen lysine salt Zentiva Italia

Take this medicine exactly as stated in this leaflet or as directed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.

Dosage

Use in adults and adolescents over 15 years of age
The recommended dose is 40 mg (corresponding to 1 sachet), taken once daily. The dose may be repeated 2–3 times daily in cases of more intense pain. Do not exceed the recommended doses.
Use the lowest effective dose for the shortest duration necessary to relieve symptoms. If you have an infection, consult your doctor immediately if symptoms (e.g. fever and pain) persist or worsen (see section 2).

Use in the elderly
If you are elderly, take the lowest possible daily dose (see section 2 “What you need to know before taking Ketoprofen lysine salt Zentiva Italia – Warnings and precautions”).

Use in patients with liver problems
If you have mild to moderate liver impairment, take the lowest possible daily dose.
Do not take this medicine if you have severe liver problems (see section 2 “What you need to know before taking Ketoprofen lysine salt Zentiva Italia – Do not take Ketoprofen lysine salt Zentiva Italia”).

Use in patients with mild to moderate kidney problems
If you have mild to moderate kidney impairment, consult your doctor, who will need to monitor you during treatment with this medicine.
Do not take this medicine if you have severe kidney problems (see section 2 “What you need to know before taking Ketoprofen lysine salt Zentiva Italia – Do not take Ketoprofen lysine salt Zentiva Italia”).

Use in children
The safety and efficacy of Ketoprofen lysine salt Zentiva Italia have not yet been established.
Do not use for prolonged periods without medical advice and do not exceed the recommended doses.

Method of administration
Ketoprofen lysine salt Zentiva Italia can be placed directly on the tongue. It dissolves with saliva, allowing it to be taken without water.
Take this medicine preferably with a full stomach, after meals.

Duration of treatment
Always use the lowest effective dose for the shortest possible time needed to control symptoms. Limit the duration of treatment to the resolution of the painful episode. Consult your doctor if symptoms recur frequently or if you have noticed any recent changes in their characteristics.
Always use the lowest effective dose for the shortest possible time needed to control symptoms, in order to reduce the risk of adverse effects.

If you take more Ketoprofen lysine salt Zentiva Italia than you should
In case of accidental overdose, contact your doctor immediately or go to the nearest hospital Emergency Department.
Cases of overdose with doses up to 2.5 g of ketoprofen have been reported. The most common symptoms of overdose include: lethargy, confusion, loss of consciousness, drowsiness, headache, dizziness, nausea, vomiting, epigastric pain (in the upper abdomen), abdominal pain and diarrhoea.
Other possible symptoms include gastrointestinal bleeding, low blood pressure (hypotension), respiratory depression, and bluish discoloration of the skin and mucous membranes (cyanosis).
There are no specific antidotes in case of ketoprofen overdose. In case of suspected massive overdose, gastric lavage is recommended, along with symptomatic and supportive treatment.
In cases of renal failure, haemodialysis (a blood purification technique using extracorporeal circulation) may help remove the circulating medicine.

If you have any doubts about how to use this medicine, consult your doctor or pharmacist.
Take this leaflet, any remaining medicine and its container with you to the hospital or doctor so that they know which medicine has been taken.

If you forget to take Ketoprofen lysine salt Zentiva Italia
If you forget to take a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take a double dose to make up for the forgotten dose.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
The most commonly observed side effects are of a gastrointestinal nature.
The side effects that may occur with Ketoprofene sale di lisina Zentiva Italia are:
Common (may affect up to 1 in 10 people)

Indigestion (dyspepsia), nausea, vomiting, abdominal pain.

Uncommon (may affect up to 1 in 100 people)

Headache, dizziness, drowsiness,
Constipation, diarrhoea, excessive gas in the gastrointestinal tract (flatulence), inflammation of the stomach lining (gastritis),
Skin rash, itching, fatigue.

Rare (may affect up to 1 in 1,000 people)

Reduction in haemoglobin, the substance that carries oxygen in the blood, due to bleeding (haemorrhagic anaemia),
Tingling and numbness in hands and feet (paraesthesia),
Blurred vision (see “Warnings and precautions”),
Ringing in the ears (tinnitus),
Asthma (bronchial inflammation and narrowing of the airways),
Inflammation of the mouth (ulcerative stomatitis),
Stomach or duodenal ulcers (peptic ulcer),
Liver problems (hepatitis, increased levels of transaminases and bilirubin in the blood, substances indicating liver function),
Increase in body weight.

Very rare (may affect up to 1 in 10,000 people)

Swelling of the face (oedema) and redness of the skin (erythema).

Frequency not known (cannot be estimated from the available data)

Reduction in the number of platelets (thrombocytopenia), severe reduction in a type of white blood cells (agranulocytosis), reduced production of blood cells by the bone marrow (bone marrow failure), reduction in haemoglobin in the blood, the substance that carries oxygen, due to destruction of red blood cells (haemolytic anaemia), reduction in the number of white blood cells (leucopenia), reduction in neutrophils, a type of white blood cells (neutropenia), reduction in haemoglobin in the blood due to reduced production of red blood cells (aplastic anaemia), increase in the number of white blood cells (leucocytosis), development of numerous small bleeding spots on the skin due to reduced platelet count (thrombocytopenic purpura),
Severe allergic reaction, including shock (anaphylactic reaction) and allergy (hypersensitivity), sudden and potentially fatal (including anaphylactic shock),
Yellowing of the skin and whites of the eyes (jaundice),
Depression, seeing and hearing things that are not real (hallucinations), confusion, mood changes, hyperexcitability, insomnia, uncontrolled body movements (seizures), dizziness, altered taste (dysgeusia), tremor, movement disorders (dyskinesia), fainting (syncope), involuntary and uncoordinated movements (hyperkinesia), swelling around the eyes due to fluid accumulation (periorbital oedema), swelling of the extremities (peripheral oedema),
Chills, tiredness (asthenia),
Inability of the heart to pump sufficient blood to meet the body's needs (heart failure), irregular heart rhythm (atrial fibrillation), awareness of your own heartbeat (palpitations), rapid heartbeat (tachycardia), high blood pressure (hypertension), low blood pressure (hypotension),
Dilation of blood vessels (vasodilation), inflammation of blood vessels (vasculitis), including small vessels (leucocytoclastic vasculitis),
Constriction of the bronchi (bronchospasm), especially in patients with known hypersensitivity to acetylsalicylic acid and other NSAIDs, inflammation of the nasal mucosa (rhinitis), shortness of breath (dyspnoea), throat swelling due to fluid accumulation (laryngeal oedema), breathing difficulty due to narrowing of the larynx (laryngospasm), acute respiratory failure (one fatal case has been reported in an asthmatic patient sensitive to acetylsalicylic acid),
Worsening of colitis and Crohn’s disease (chronic inflammatory bowel diseases), gastrointestinal bleeding (gastrointestinal haemorrhage), gastrointestinal perforation (sometimes fatal, particularly in the elderly, see “Warnings”), gastric ulcer (stomach lesion), oral ulceration, duodenal ulcer (lesion in the first part of the intestine), duodenal perforation, heartburn (gastric pyrosis), swelling of the mouth (oedema), inflammation of the pancreas (pancreatitis), presence of digested blood in stools (melaena), vomiting blood (haematemesis), abdominal discomfort, colitis, hyperchlorhydria (excess stomach acid), stomach pain (dyspepsia), severe damage to the stomach lining without perforation leading to bleeding (erosive gastritis), swelling of the tongue (oedema),
Excessive sensitivity reaction to sunlight or UV lamps (photosensitivity), loss of hair and body hair (alopecia), urticaria, swelling of the face, lips, mouth, tongue or throat which may cause difficulty in breathing and swallowing (angioedema), rare skin condition with blisters and bleeding of lips, eyes, mouth, nose and genitals (Stevens-Johnson syndrome), severe skin disease (Lyell’s syndrome, toxic epidermal necrolysis), oedema (fluid retention), rash (exanthema), maculopapular rash (skin eruption with spots), purpura (purple spots on the skin due to abnormal blood accumulation), generalised acute exanthematous pustulosis (skin eruption with formation of pus-filled blisters), dermatitis (skin irritation),
Reduced kidney function (acute renal failure), tubulo-interstitial nephritis, kidney inflammation (nephritis and nephrotic syndrome), kidney disorder causing loss of protein in urine (nephrotic syndrome), inflammatory kidney disease (glomerular nephritis), accumulation of water and sodium causing swelling (fluid/sodium retention with possible oedema), acute tubular necrosis and renal papillary necrosis, reduced urine production (oliguria), abnormalities in kidney function tests, presence of blood in urine (haematuria),
Inflammation of the membranes covering the brain and spinal cord, not caused by infection (aseptic meningitis), inflammation of the lymphatic vessels (lymphangitis),
Increased potassium levels in the blood (hyperkalaemia), decreased sodium levels in the blood (hyponatraemia).

Following the instructions provided in this leaflet reduces the risk of side effects.
Reporting of side effects
If you experience any side effect, including those not listed in this leaflet, please inform your doctor or pharmacist. You can also report side effects directly via the national reporting system at www.aifa.gov.it/content/segnalazioni-reazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Ketoprofene lysine salt Zentiva Italia

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the packaging after "Exp.".
The expiry date refers to the last day of that month.
Do not dispose of any medicine via wastewater or household waste. Ask your pharmacist how to
dispose of medicines you no longer use. This will help protect the environment.

6. Package contents and other information

What Ketoprofene sale di lisina Zentiva Italia contains
The active substance is ketoprofene lysine salt.
Each sachet contains 40 mg of ketoprofene lysine salt (equivalent to 25 mg of ketoprofen).
The other components are: mannitol, xylitol, lime flavour, lemon flavour, frescofort flavour,
aspartame, talc, butylated methacrylate copolymer, magnesium stearate, colloidal hydrated silica,
hypromellose, stearic acid, povidone, sodium lauryl sulfate.
Description of the appearance of Ketoprofene sale di lisina Zentiva Italia and package contents
Ketoprofene sale di lisina Zentiva Italia is presented as an oral granulate.
Pack sizes: 12 sachets, 24 sachets or 30 sachets.
Marketing Authorization Holder
Zentiva Italia S.r.l. Via P. Paleocapa, 7 20121 Milano
Manufacturer
Doppel Farmaceutici S.r.l. - Via Volturno, 48 - 20089 Quinto De’ Stampi - Rozzano (MI)