Cardiophyt

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT CARDIOPHYT

Composition:

Active substances: 1 ml of the preparation contains a complex tincture made from a mixture of medicinal plant raw materials (7 mg of spring adonis herb (Adonidis vernalis herba); 7 mg of amorpha fruit (Amorphae fructus); 7 mg of hawthorn flowers (Crataegi flos); 7 mg of elder flowers (Sambuci nigrae flos); 10.5 mg of valerian rhizomes with roots (Valerianae rhizomata cum radicibus); 7 mg of melilot herb (Meliloti herba); 10.5 mg of horse chestnut seeds (Hippocastani semina); 3.5 mg of nettle leaf (Urticae folium); 7 mg of lily-of-the-valley leaves and flowers (Convallariae folia et flores); 7 mg of peppermint leaf (Menthae piperitae folium); 7 mg of licorice roots (Liquiritiae radix); 7 mg of motherwort herb (Leonuri herba); 5.5 mg of white mistletoe leaves (Visci albi folium); 7 mg of creeping thyme herb (Serpylli herba)) (1:10) (extraction agent – ethanol 40%).

Pharmaceutical form. Complex tincture.

A clear, dark brown liquid with a pleasant odor. The presence of sediment is permissible.

Pharmacotherapeutic group. Agents used in cardiology. Other combined cardiovascular drugs. ATC code C01EX.

Pharmacological properties.

Pharmacodynamics.

For functional cardiovascular disorders, CARDIOPHYT exerts cardiotonic, antiarrhythmic, and mild hypotensive effects. In organic cardiovascular diseases as part of combination therapy, CARDIOPHYT optimizes the effects of antianginal, antihypertensive, and antiarrhythmic drugs.

The preparation produces a mild sedative effect, reduces manifestations of vegetative disorders, improves the general condition of patients and tolerance to physical exertion, promoting optimal work capacity. When used during the daytime, CARDIOPHYT does not cause drowsiness or general lethargy.

Pharmacokinetics.

Considering that the components of the drug are of plant origin and the drug's effect is determined by the combined action of its components, pharmacokinetic studies have not been conducted.

Clinical characteristics.

Indications. Vegetative-vascular dystonia, cardiac neurosis. As part of complex treatment of ischemic heart disease (exertional angina class I–II), hypertensive disease (stages I–II), paroxysmal supraventricular tachycardia.

Contraindications. Hypersensitivity to the components of the drug or to other plants of the Lamiaceae family, as well as known allergy to celery and birch pollen (possible cross-reaction). Gastric and duodenal peptic ulcer, cholestatic disorders, severe liver and kidney diseases, depression, arterial hypotension, bradycardia, acute myocarditis, endocarditis, pericarditis, increased blood coagulation. History of alcoholism. Concomitant use of medicinal products containing ethanol, neuroleptics, tranquilizers; consumption of alcoholic beverages.

Interaction with other medicinal products and other forms of interactions. The drug may enhance the effects of antianginal, antihypertensive, antiarrhythmic, sedative, hypnotic, analgesic, spasmolytic agents, cardiac glycosides, neuroleptics, tranquilizers, and direct and indirect anticoagulants.

Prolonged concomitant use with cardiac glycosides, antiarrhythmic drugs (quinidine), adrenocorticosteroids, thiazide and loop diuretics, or laxatives may lead to disturbances in water-electrolyte balance.

Concomitant use of the drug with aminoglycoside antibiotics should be avoided due to increased nephrotoxic effect of aminoglycosides.

Special precautions for use.

Prolonged use of the drug in high doses (more than two months) is not recommended, as it may lead to disturbances in water-electrolyte balance due to the presence of licorice roots in the drug formulation.

Use during pregnancy or breastfeeding. Contraindicated during pregnancy. If it is necessary to use the drug, breastfeeding should be discontinued.

Ability to affect reaction speed when driving or operating machinery. During treatment with this drug, activities requiring heightened attention and rapid psychomotor reactions (such as driving vehicles or operating complex machinery) should be avoided.

Dosage and Administration.

Shake before use. For oral use in adults: 1 teaspoon (5 ml) 2–3 times a day, 30 minutes before or 1 hour after meals. In acute disease forms or stressful situations, the dose may be doubled. The preparation can be diluted with water in a ratio of 1:3 or 1:5. Duration of treatment and frequency of treatment courses are determined by a physician depending on the severity of the disease and the therapeutic effect achieved.

Children. The drug is contraindicated in children.

Overdose. Overdose is accompanied by acute alcohol intoxication; symptoms are similar to those of ethanol poisoning. When blood alcohol concentration reaches 3–4 g/L (300–400 mg%), pronounced intoxication develops.

In addition, overdose may cause decreased arterial pressure, headache, dizziness, gastrointestinal disturbances, and increased severity of adverse reactions.

Treatment: gastric lavage, use of adsorbents, symptomatic therapy.

Prolonged use in high doses may lead to disturbances in water-electrolyte balance.

Side effects.

The product is generally well tolerated by patients. However, due to its multi-component composition, in individual cases—usually in the presence of individual hypersensitivity to any component of the product or in case of violation of the recommended dosage regimen—very rare development of allergic reactions may occur, including hyperemia, itching, rash (including petechial rash), urticaria, angioneurotic edema; gastrointestinal disorders, including nausea, vomiting, abdominal pain, diarrhea; bradycardia. If any adverse reactions occur, medical advice should be sought.

Shelf life. 3 years.

Do not use the medicinal product after the expiry date stated on the packaging.

Storage conditions. In the original packaging at a temperature not exceeding 25 °C, in a place inaccessible to children.

Packaging. 100 ml in bottles No. 1; 100 ml in flacons No. 1.

Dispensing category. Over-the-counter.

Manufacturer. LLC "Scientific and Production Pharmaceutical Company "EYM".

Manufacturer's address. 20 lit. "A-5", Kharkivs'kykh Dyviziy St., Kharkiv, Kharkiv region, 61091, Ukraine.