Tachifluactiv

Package leaflet: Information for the user

TACHIFLUACTIV 400 mg / 200 mg effervescent tablets, 400 mg / 200 mg effervescent granules

Paracetamol / Vitamin C
Please read this leaflet carefully before taking this medicine because it contains important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has instructed you.

• Keep this leaflet. You may need to read it again.
• If you need more information or advice, consult your pharmacist.
• If you experience any side effects, including those not listed in this leaflet, contact your doctor or pharmacist. See section 4.
• Contact your doctor if you do not notice any improvement or if your symptoms worsen after 3 days of treatment.

Contents of this leaflet:

1. What Tachifluactiv is and what it is used for
2. What you need to know before taking Tachifluactiv
3. How to take Tachifluactiv
4. Possible side effects
5. How to store Tachifluactiv
6. Contents of the pack and other information

1. What Tachifluactiv is and what it is used for

Tachifluactiv contains as active ingredients paracetamol and vitamin C:

• paracetamol acts by reducing fever (antipyretic) and relieving pain (analgesic);
• vitamin C exerts a protective effect on the vascular system and activates the body's defense mechanisms.

Tachifluactiv is used in adults and children over 6 years of age for:

• treatment of flu-like symptoms and febrile conditions of any type and origin due to exanthematic diseases (infectious diseases generally more common in children and adolescents), colds, infectious diseases or of viral nature;
• headache, neuralgia, muscle and joint pain, and menstrual pain.

Consult your doctor if you do not feel better or if you feel worse after 3 days of treatment.

2. What you need to know before taking Tachifluactiv

Do not take Tachifluactiv

• if the person taking the medicine is allergic to paracetamol or vitamin C or to any of the other ingredients of this medicine (listed in section 6).
• if the person is under 6 years of age (children).
• if the person taking the medicine suffers from severe haemolytic anaemia (a disease caused by the destruction of certain blood cells, red blood cells).
• if the person taking the medicine has liver diseases that severely impair its function (severe hepatic insufficiency).
• if the person taking the medicine suffers from phenylketonuria (see section “Tachifluactiv effervescent granules contain sodium, maltitol and aspartame”).

Warnings and precautions
Talk to your doctor or pharmacist before taking Tachifluactiv

• if the person taking the medicine suffers from glucose-6-phosphate dehydrogenase deficiency (a substance normally present in the human body, whose deficiency may cause a blood disorder),
• if the person taking the medicine has or has had kidney disease (renal insufficiency) or liver disease (hepatic insufficiency) or suffers from Gilbert’s syndrome,
• if the person taking the medicine is undergoing concomitant treatment with analgesic medicines (painkillers), antipyretics (medicines to reduce fever) or anti-inflammatory drugs.

During treatment with Tachifluactiv, inform your doctor immediately if:
You suffer from serious illnesses, including severe renal impairment or sepsis (when bacteria and their toxins circulate in the blood causing organ damage) or malnutrition, chronic alcoholism, or if you are also taking flucloxacillin (an antibiotic). In patients with these conditions, a serious condition called metabolic acidosis (an abnormality in blood and body fluids) has been reported when paracetamol is used at regular doses for prolonged periods or when paracetamol is taken together with flucloxacillin. Symptoms of metabolic acidosis may include: severe breathing difficulties with rapid deep breathing, drowsiness, nausea and vomiting.
Do not take this medicine for more than three consecutive days without consulting your doctor.
Use of high doses and/or prolonged use
Taking high doses and/or prolonged use of this medicine may cause liver disorders (hepatopathy) and even serious alterations affecting the kidneys and blood. In such cases, your doctor will periodically monitor, through appropriate tests, liver and kidney function and blood composition. Before taking this medicine, inform your doctor if the person taking it suffers from kidney or liver disease.
Children and adolescents
Do not give Tachifluactiv to children under 6 years of age. See section “Do not take Tachifluactiv”.
Other medicines and Tachifluactiv
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
In particular, inform your doctor if the person taking the medicine is taking:

• medicines containing paracetamol. During treatment with paracetamol, before taking any other medicine check that it does not contain paracetamol, as serious adverse effects may occur if paracetamol is taken in high doses;
• anticoagulants, which are medicines used to make the blood less likely to clot. Your doctor may reduce their dosage;
• flucloxacillin (an antibiotic), due to a serious risk of blood and fluid disorder (called metabolic acidosis) that must be urgently treated (see section 2);
• medicines or substances that, during chronic treatment, alter liver function, for example:
• rifampicin (an antibiotic);
• cimetidine (a medicine used in the treatment of stomach ulcers);
• antiepileptics (medicines used to treat epilepsy), for example glutethimide, phenobarbital, carbamazepine.
  The use of these medicines with Tachifluactiv requires close medical supervision.

Do not take this medicine together with other analgesic medicines (painkillers), antipyretics (medicines to reduce fever) or anti-inflammatory drugs.
Interference with blood tests
If the person taking the medicine needs to undergo blood tests, keep in mind that administration of paracetamol may interfere with the measurement of uric acid levels (uricemia) and blood glucose levels (glycemia).
Pregnancy and breastfeeding
If you are pregnant, think you may be pregnant, planning to become pregnant, or are breastfeeding, ask your doctor or pharmacist for advice before taking this medicine.
If necessary, Tachifluactiv may be used during pregnancy. It is advisable to use the lowest possible dose that relieves pain and/or fever and to take it for the shortest possible time. Contact your doctor or midwife if pain and/or fever do not decrease or if you need to take the medicine more frequently.
Although clinical studies in breastfeeding patients have not shown particular contraindications to the use of paracetamol nor caused adverse effects in the infant, it is recommended to administer the medicine during breastfeeding only when strictly necessary and under direct medical supervision.
Driving and using machines
Tachifluactiv does not affect the ability to drive or use machinery.
Tachifluactiv effervescent tablets contain sodium
This medicine contains 384.295 mg of sodium (the main component of table salt) per tablet.
This corresponds to 19.2% of the maximum daily dietary intake recommended for an adult.
Tachifluactiv effervescent granules contain:
sodium: This medicine contains 281.91 mg of sodium (the main component of table salt) per sachet.
This corresponds to 14.1% of the maximum daily dietary intake recommended for an adult. This should be taken into account in people with reduced kidney function or those following a low-sodium diet.
maltitol: If your doctor has diagnosed you with an intolerance to certain sugars, contact them before taking this medicine.
aspartame: This medicine contains 13 mg of aspartame per dose, equivalent to 13 mg/5900 mg.
Aspartame is a source of phenylalanine. It may be harmful if you suffer from phenylketonuria, a rare genetic disorder causing accumulation of phenylalanine because the body cannot properly eliminate it.

3. How to take Tachifluactiv

Take this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Adults
The recommended dose is 1 effervescent tablet or 1 sachet, 3-4 times daily.
Use in children aged between 6 and 12 years
The recommended dose is half an effervescent tablet or half a sachet, 3-4 times daily.
Elderly
The dose should be carefully determined by the doctor, who will assess whether a reduction of the above-mentioned doses is necessary.
Warning: Do not exceed the recommended doses.
Dissolve the effervescent tablet or effervescent granules in a glass of water and take with food.
Instructions for using the sachets:
The granules contained in the sachet are divided into two parts.
To obtain a full dose, open the sachet as shown in fig. 1. To obtain a half dose, open the sachet as shown in fig. 2.

Duration of treatment
Do not take Tachifluactiv for more than 3 consecutive days without consulting your doctor. Your doctor must evaluate whether treatment beyond 3 consecutive days is necessary.
Consult your doctor if symptoms recur repeatedly or if you notice any recent changes in their characteristics.
If you take more Tachifluactiv than you should
In case of accidental ingestion or overdose of Tachifluactiv, contact your doctor immediately or go to the nearest hospital.
Symptoms
Following accidental ingestion of very high doses of paracetamol, symptoms that may generally appear within the first 12–48 hours include:

• anorexia (loss of appetite or reduced appetite),
• nausea,
• vomiting,
• severe deterioration in general condition,
• yellowish skin and eyes (increased bilirubin in the blood),
• changes in blood laboratory values,
• coma and death.

Treatment
Depending on the nature and severity of symptoms, the doctor will administer appropriate supportive therapy.
Note for healthcare professionals: the specific antidote in case of paracetamol poisoning is intravenous N-acetylcysteine: the dosage regimen is 150 mg/kg intravenously in glucose solution over 15 minutes, followed by 50 mg/kg over the next 4 hours and 100 mg/kg over the subsequent 16 hours, for a total dose of 300 mg/kg over 20 hours.
If you forget to take Tachifluactiv
Do not take a double dose to make up for a missed dose.
If you stop treatment with Tachifluactiv
If you have any doubts about how to use this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody will experience them.
If you experience any of the following side effects, STOP taking this medicine and contact your doctor
immediately:

• allergic reactions such as:
  • swelling of the throat (laryngeal oedema),
  • swelling of hands, feet, ankles, face, lips, tongue and/or throat (angioedema),
  • severe allergic reaction (anaphylactic shock).

In addition, patients taking this medicine may experience the following side effects, for which insufficient data
are available to determine the frequency.
Effects related to blood

• decreased number of platelets in the blood (thrombocytopenia),
• decreased number of white blood cells in the blood (leucopenia/agranulocytosis),
• reduced haemoglobin in the blood, the substance that carries oxygen in the blood (anaemia).

Effects related to the nervous system

• dizziness.

Effects related to the stomach and intestines

• stomach and intestinal disturbances.

Effects related to the liver

• changes in liver function,
• inflammation of the liver (hepatitis).

Effects related to the skin and subcutaneous tissue

• red spots, blistering lesions with areas of skin detachment, blisters, skin eruptions (erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis). Very rare cases of severe skin reactions have been reported.

Effects related to the kidneys and urinary tract

• reduced kidney function (acute renal failure),
• inflammation of the kidneys (interstitial nephritis),
• blood in the urine (haematuria),
• cessation or reduction in urine production (anuria).

Effects related to metabolism and nutrition

• severe condition that may make the blood more acidic (called metabolic acidosis), in patients with a serious underlying disease who are using paracetamol (see section 2) (frequency not known, cannot be estimated from available data).

Reporting of side effects
If you experience any side effects, including those not listed in this leaflet, please inform your doctor or pharmacist.
You can also report side effects directly via the national reporting system at https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Tachifluactiv

Keep this medicine out of the sight and reach of children.
Effervescent tablets: store below 25 °C.
Effervescent granules: this medicine requires no special storage conditions.
Do not use this medicine after the expiry date stated on the packaging after "Exp.". The expiry date refers to the last day of that month.
Do not dispose of medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. This will help protect the environment.

6. Package contents and other information

What Tachifluactiv effervescent tablets contain

• The active ingredients are: paracetamol and vitamin C (ascorbic acid). Each effervescent tablet contains 400 mg of paracetamol and 200 mg of vitamin C.
• The other components are: sodium bicarbonate, citric acid, mannitol, fumaric acid, sodium saccharin, lemon flavour, polyvinylpyrrolidone, sodium docusate (see section “Tachifluactiv effervescent tablets contain sodium”).

What Tachifluactiv effervescent granules contain

• The active ingredients are: paracetamol and vitamin C (ascorbic acid). Each sachet of effervescent granules contains 400 mg of paracetamol and 200 mg of vitamin C.
• The other components are: sodium bicarbonate, citric acid, mannitol, sodium docusate, citrus flavour, maltitol, aspartame (see section “Tachifluactiv effervescent granules contain”).

Description of the appearance of Tachifluactiv and contents of the pack
Tachifluactiv effervescent tablets are white, round effervescent tablets.
The tablets are packaged in blisters, in a carton containing 12 effervescent tablets.
Tachifluactiv effervescent granules are presented as a white-ivory, free-flowing effervescent granule contained in divisible sachets. Each package contains 20 divisible sachets.
Not all pack sizes may be marketed.

Marketing Authorization Holder
Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.p.A.
Viale Amelia 70, 00181 Rome

Manufacturer
Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.p.A.
Via Vecchia del Pinocchio 22, 60131 Ancona

N D E S
Influenza-like illnesses are often characterized by joint pain, fever, headache, cold symptoms sometimes associated with reduced hearing. In these cases, as well as in febrile conditions of various origins, it is important to ensure rest, generous fluid intake, and consumption of light meals rich in fruit and vegetables.

Package leaflet: information for the user

TACHIFLUACTIV ADULTS 500 mg / 200 mg effervescent tablets

Paracetamol / Vitamin C
Please read this leaflet carefully before taking this medicine, as it contains important
information for you.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has instructed you.

• Keep this leaflet. You may need to read it again.
• If you need more information or advice, consult your pharmacist.
• If you experience any side effects, including those not listed in this leaflet, contact your doctor or pharmacist. See section 4.
• Consult your doctor if you do not notice any improvement or if your symptoms worsen after 3 days of treatment.

Contents of this leaflet:

1. What Tachifluactiv is and what it is used for
2. What you need to know before taking Tachifluactiv
3. How to take Tachifluactiv
4. Possible side effects
5. How to store Tachifluactiv
6. Contents of the pack and other information

1. What Tachifluactiv is and what it is used for

Tachifluactiv contains as active ingredients paracetamol and vitamin C:

• paracetamol acts by reducing fever (antipyretic) and relieving pain (analgesic);
• vitamin C exerts a protective effect on the vascular system and stimulates the body's defense mechanisms.

Tachifluactiv is used in adults for:

• treatment of flu-like symptoms and febrile conditions of any kind due to exanthematic diseases (infectious diseases generally more common in children and adolescents), colds, or infectious diseases;
• headache, neuralgia, muscle and joint pain, and menstrual pain.

Consult a doctor if you do not feel better or feel worse after 3 days of treatment.

2. What you should know before taking Tachifluactiv

Do not take Tachifluactiv

• if the person taking the medicine is allergic to paracetamol or vitamin C or to any of the other ingredients of this medicine (listed in section 6)
• if the person is under 18 years of age (children and adolescents).

Warnings and precautions
Talk to your doctor or pharmacist before taking Tachifluactiv:

• if the person taking the medicine chronically consumes alcohol or uses it excessively (3 or more alcoholic drinks per day)
• if the person taking the medicine suffers from anorexia (an eating disorder characterized by lack or reduced appetite)
• if the person taking the medicine suffers from bulimia (an eating disorder in which a person ingests excessive amounts of food and then resorts to various methods to eliminate it)
• if the person taking the medicine suffers from cachexia (a condition characterized by extreme thinness, reduced muscle mass, and thinning of the skin due to chronic illness)
• if the person taking the medicine has long-term inadequate nutrition (chronic malnutrition)
• if the person taking the medicine suffers from dehydration (severe loss of water/fluids from the body)
• if the person taking the medicine suffers from hypovolemia (reduced blood volume in circulation)
• if the person taking the medicine has liver diseases that reduce liver function (hepatic insufficiency, acute hepatitis, Gilbert's syndrome)
• if the person taking the medicine has or has had kidney disease (renal insufficiency)
• if the person taking the medicine is undergoing concomitant treatment with medicines that affect liver function (see “Other medicines and Tachifluactiv”)
• if the person taking the medicine has glucose-6-phosphate dehydrogenase deficiency (a substance normally present in the human body; deficiency may cause a blood disorder)
• if the person taking the medicine suffers from haemolytic anaemia (a disease caused by destruction of certain blood cells, red blood cells).

During treatment with Tachifluactiv, inform your doctor immediately if:
You suffer from serious illnesses, including severe kidney impairment or sepsis (when bacteria and their toxins circulate in the blood causing organ damage), or malnutrition, chronic alcoholism, or if you are also taking flucloxacillin (an antibiotic). In patients with these conditions, a serious condition called metabolic acidosis (an abnormality in blood and body fluids) has been reported when paracetamol is used regularly for prolonged periods or when paracetamol is taken together with flucloxacillin. Symptoms of metabolic acidosis may include: severe breathing difficulties with deep and rapid breathing, drowsiness, nausea, and vomiting.

Use of high doses and/or prolonged use
Taking high doses and/or prolonged use of this medicine may cause liver disorders (hepatopathy) and even serious adverse effects on the kidneys and blood. In such cases, your doctor will periodically monitor liver and kidney function and blood composition through appropriate tests. Before taking this medicine, inform your doctor if the person taking it suffers from kidney or liver disease.

Children and adolescents
Do not give Tachifluactiv to children and adolescents (0–18 years). See section “Do not take Tachifluactiv”.

Other medicines and Tachifluactiv
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

In particular, inform your doctor if the person taking the medicine is taking:

• medicines containing paracetamol. During treatment with paracetamol, check that any other medicine you take does not contain paracetamol, as serious adverse effects may occur if paracetamol is taken in high doses;
• medicines that slow gastric emptying (e.g. anticholinergics, opioids), as these medicines delay the effect of Tachifluactiv;
• medicines that accelerate gastric emptying (e.g. prokinetics), as these medicines accelerate the effect of Tachifluactiv;
• cholestyramine (a medicine used to reduce cholesterol levels in the blood), as it reduces the effect of paracetamol;
• chloramphenicol (an antibiotic), as it may increase the risk of adverse effects;
• anticoagulants, which are medicines used to make the blood less prone to clotting. In this case, especially during prolonged treatment and high-dose paracetamol (4 g daily for at least 4 days), take Tachifluactiv only under strict medical supervision;
• flucloxacillin (an antibiotic), due to a serious risk of blood and fluid abnormalities (called metabolic acidosis) requiring urgent treatment (see section 2);
• medicines or substances that chronically alter liver function, for example:
  • rifampicin (an antibiotic);
  • cimetidine (a medicine used to treat stomach ulcers);
  • antiepileptics (medicines used to treat epilepsy), such as glutethimide, phenobarbital, carbamazepine;
  • chronic alcohol use;
  • zidovudine (a medicine for the treatment of HIV).
    The use of these medicines with Tachifluactiv requires close medical monitoring.

Interference with blood tests
If the person taking the medicine needs to undergo blood tests, note that administration of paracetamol may interfere with the measurement of serum uric acid and blood glucose levels.

Tachifluactiv and alcohol
Take Tachifluactiv with caution if you chronically consume alcohol or use it excessively (3 or more alcoholic drinks per day), as there is a risk of toxicity (see sections “Warnings and precautions” and “If you take more Tachifluactiv than you should”).

Pregnancy and breastfeeding
If you are pregnant, think you may be pregnant, planning to become pregnant, or are breastfeeding, consult your doctor or pharmacist before taking this medicine.

If necessary, Tachifluactiv may be used during pregnancy. It is advisable to use the lowest possible dose that relieves pain and/or fever, and to take it for the shortest possible time. Contact your doctor or midwife if pain and/or fever do not decrease or if you need to take the medicine more frequently.

Although clinical studies in breastfeeding patients have not shown particular contraindications to the use of paracetamol nor caused adverse effects in the infant, it is recommended to administer the medicine during breastfeeding only when strictly necessary and under direct medical supervision.

Driving and using machines
Tachifluactiv does not affect the ability to drive or use machinery.

Tachifluactiv contains

Sodium: this medicine contains 280.197 mg of sodium (the main component of table salt) per effervescent tablet. This corresponds to 14% of the maximum recommended daily dietary intake for an adult. This should be taken into account in individuals with impaired kidney function or those on a low-sodium diet.

Sorbitol: this medicine contains 278 mg of sorbitol per dose, equivalent to 248/3000 mg. If your doctor has diagnosed an intolerance to certain sugars, contact them before taking this medicine.

Sunset Yellow (E110): may cause allergic reactions.

3. How to take Tachifluactiv

Take this medicine exactly as stated in this leaflet or as instructed by your
doctor or pharmacist. If you are in doubt, consult your doctor or pharmacist.
Adults
The recommended dose is 1 effervescent tablet at a time, which may be repeated if necessary after 4 hours, without
exceeding 6 doses per day.
In the case of severe pain or high fever, take 2 effervescent tablets, repeating if necessary after at least 4 hours.
Caution: do not exceed the recommended doses.
Dissolve the effervescent tablet in a glass of water and drink.
Duration of treatment
Do not take Tachifluactiv for more than 3 consecutive days without consulting your doctor. Your doctor must assess
the need for treatment lasting longer than 3 consecutive days.
Consult your doctor if symptoms recur frequently or if you notice any recent changes in their characteristics.
If you take more Tachifluactiv than you should
In case of accidental ingestion/overdose of Tachifluactiv, contact your doctor immediately or go to the nearest hospital.
Symptoms
Following accidental ingestion of very high doses of paracetamol, symptoms generally appearing within the first 12–48 hours may include:

• anorexia (loss or reduction of appetite)
• nausea
• vomiting
• profound deterioration in general condition
• yellowish discoloration of the skin and eyes (increased bilirubin in the blood)
• alterations in blood laboratory values (elevated levels of liver transaminases, lactate dehydrogenase, and bilirubin; reduced prothrombin levels)
• coma and death.
  Overdose of paracetamol increases the risk of poisoning and can lead to death, especially in the following cases:
• if the patient has liver disease
• chronic alcoholism
• if the patient has long-term inadequate nutrition (chronic malnutrition)
• if the patient is taking medicines or substances that increase liver enzyme activity.

Treatment
The doctor will provide appropriate supportive therapy based on the nature and severity of the symptoms.
Note for healthcare professionals: the specific antidote in case of paracetamol poisoning is N-acetylcysteine administered intravenously: the dosage is 150 mg/kg i.v. in glucose solution over 15 minutes, followed by 50 mg/kg over the next 4 hours and 100 mg/kg over the subsequent 16 hours, for a total of 300 mg/kg over 20 hours.
If you forget to take Tachifluactiv
Do not take a double dose to make up for the forgotten tablet.
If you stop treatment with Tachifluactiv
If you have any doubts about using this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody will experience them.
If you experience any of the following side effects, STOP treatment with this medicine and contact your doctor immediately:

• allergic reactions such as:
  • skin redness accompanied by itching (urticaria)
  • swelling of the throat (laryngeal oedema)
  • swelling of hands, feet, ankles, face, lips, tongue and/or throat (angioedema)
  • severe allergic reaction (anaphylactic shock).

In addition, patients taking this medicine may experience the following side effects, for which there are insufficient data to determine frequency.

Effects on blood

• decrease in the number of platelets in the blood (thrombocytopenia)
• decrease in the number of white blood cells in the blood (leucopenia/agranulocytosis)
• decrease in haemoglobin in the blood, the substance that carries oxygen in the blood (anaemia).

Effects on the nervous system

• dizziness.

Effects on the stomach and intestines

• stomach and intestinal disturbances.

Effects on the liver

• altered liver function
• inflammation of the liver (hepatitis).

Effects on the skin and subcutaneous tissue

• red spots, blistering lesions with areas of skin detachment, blisters, skin rashes (erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis). Very rare cases of serious skin reactions have been reported.

Effects on the kidneys and urinary tract

• reduced kidney function (acute renal failure)
• inflammation of the kidneys (interstitial nephritis)
• blood in the urine (haematuria)
• cessation or reduction in urine production (anuria).

Effects on metabolism and nutrition

• severe condition that may make the blood more acidic (called metabolic acidosis), in patients with a severe illness who use paracetamol (see section 2) (frequency not known, cannot be estimated based on available data).

Reporting of side effects
If you experience any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Tachifluactiv

Keep this medicine out of the sight and reach of children.
This medicine does not require any special storage conditions.
Do not use this medicine after the expiry date stated on the packaging after "Exp". The expiry date refers to the last day of that month.
Do not dispose of any medicine via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. This will help protect the environment.

6. Package contents and other information

What Tachifluactiv contains

• The active substances are: paracetamol and vitamin C (ascorbic acid). Each effervescent tablet contains 500 mg of paracetamol and 200 mg of vitamin C.
• The other components are: anhydrous citric acid, sodium bicarbonate, sodium anhydrous carbonate, sodium docusate, sorbitol, sunset yellow (E110) (see section “Tachifluactiv contains”), acesulfame K, orange flavour, simeticone emulsion.

Description of the appearance of Tachifluactiv and pack contents
Tachifluactiv is presented as round, pink-coloured effervescent tablets. The tablets are packaged in blisters, packed in cartons containing 12 or 18 effervescent tablets.
It is possible that not all pack sizes are marketed.

Marketing Authorization Holder
Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.p.A.
Viale Amelia 70, 00181 Roma

Manufacturer
Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.p.A.
Via Vecchia del Pinocchio 22, 60131 Ancona

N D E S
Influenza-like conditions are often characterized by joint pain, fever, headache, cold symptoms sometimes associated with reduced hearing. In these cases, as well as in febrile conditions of various origins, it is important to ensure rest, generous fluid intake, and consumption of light meals rich in fruit and vegetables.