Package leaflet: Information for the patient

ALGOPIRINDOL 600 mg film-coated tablets

Ibuprofen
Generic medicine
Please read all of this leaflet carefully before you take this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again.
If you have any questions, ask your doctor or pharmacist.
This medicine has been prescribed for you only. Do not give it to other people, even if they have the same symptoms as yours, because it could be harmful.
If you experience any side effects, including those not listed in this leaflet, talk to your doctor, pharmacist, or nurse. See section 4.

Contents of this leaflet:

What ALGOPIRINDOL is and what it is used for
What you need to know before taking ALGOPIRINDOL
How to take ALGOPIRINDOL
Possible side effects
How to store ALGOPIRINDOL
Contents of the pack and other information

1. What ALGOPIRINDOL is and what it is used for

ALGOPIRINDOL contains ibuprofen, which belongs to a class of medicines called NSAIDs (non-steroidal
anti-inflammatory drugs). These medicines work by reducing pain and swelling caused by inflammation in
conditions such as:

osteoarthritis (a degenerative disease affecting the joints) in various parts of the body;
inflammation of the muscles (myositis), of the muscles and connective tissues (fibrositis), of the tendons (tenosynovitis), of nerve roots and nerves (radiculoneuritis), and of fibrous tissues surrounding the joint (scapulohumeral periarthritis);
back pain;
sciatica (leg pain caused by irritation of the sciatic nerve);
rheumatoid arthritis (a progressive, chronic autoimmune disease affecting the joints), including juvenile rheumatoid arthritis or Still's disease;
sprains or strains;

ALGOPIRINDOL can also be used in other painful conditions such as toothache following tooth extraction or
other dental procedures, postoperative pain, postpartum pain, menstrual pain, and headache, including migraine.

2. What you need to know before taking ALGOPIRINDOL

Do not take ALGOPIRINDOL

if you are allergic to the active substance or to any of the other ingredients of ALGOPIRINDOL (listed in section 6);
if you have previously experienced allergic reactions such as asthma, nasal discharge, itchy skin rash, or swelling of the lips, face, tongue, or throat after taking

medicines containing acetylsalicylic acid (such as aspirin) or other painkillers or
anti-inflammatory medicines (NSAIDs);

if you have previously suffered from stomach or small intestine (duodenum) ulcers or bleeding related to previous use of painkillers or anti-inflammatory medicines (NSAIDs);
if you currently have a stomach or small intestine (duodenum) ulcer or bleeding, or if you have experienced two or more episodes of such conditions;
if you have a disease that increases your tendency to bleed;
if you have severe liver, kidney, or heart problems (including coronary artery disease);
if you are a woman in the last three months of pregnancy;
if you have significant dehydration (caused by vomiting, diarrhoea, or insufficient fluid intake);
if you have active bleeding (including bleeding in the brain);
if you suffer from an unknown-origin disease causing abnormal formation of red blood cells;

Do not use ALGOPIRINDOL in children under 12 years of age.
Warnings and precautions
Exercise particular caution when taking ALGOPIRINDOL.
Serious skin reactions have been reported with ibuprofen treatment, including exfoliative dermatitis,
erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP).
Stop using ALGOPIRINDOL and contact your doctor immediately if you notice any of the symptoms
related to these serious skin reactions described in section 4.
Consult your doctor or pharmacist before taking ALGOPIRINDOL:

if you suffer from systemic lupus erythematosus (SLE) or other autoimmune diseases, or mixed connective tissue disease—conditions affecting connective tissue causing joint or muscle pain, skin changes, and problems in other organs;
if you have a hereditary blood pigment (haemoglobin) disorder (porphyria);
if you are in the first six months of pregnancy;
breastfeeding;
if you suffer from chronic inflammatory bowel diseases such as ulcerative colitis (inflammation of the colon with ulcers), digestive tract inflammation (Crohn's disease), or other stomach or intestinal diseases;
if you suffer from disorders affecting red blood cell formation;
if you have problems with normal blood clotting mechanisms;
if you suffer from allergies, hay fever, asthma, chronic swelling of nasal mucosa, sinuses, or adenoids, or chronic obstructive respiratory diseases, as there is an increased risk of airway narrowing and breathing difficulties (bronchospasm);
if you have nasal inflammation (chronic rhinitis) or nasal polyps;
if you have previously experienced swelling of the face, throat, lips, or other body parts (angioedema);
if you suffer from liver, kidney, heart problems, or high blood pressure;
if you have recently undergone surgery;
if you are elderly, as you have a higher likelihood of developing adverse events with this medicine, particularly stomach and intestinal bleeding and perforations, which can be life-threatening (see the section below titled "BE CAREFUL" regarding gastrointestinal risks);
if you have chickenpox, as pain and anti-inflammatory medicines (NSAIDs) may worsen the severity of skin lesions caused by it. In such cases, your doctor may advise against using this medicine;
if you are a dehydrated adolescent or elderly person, as you are more likely to develop kidney problems;
if you have an infection—see the section "Infections" below.

Signs of an allergic reaction to ibuprofen have been reported, including breathing problems, facial and neck swelling (angioedema), and chest pain. Immediately discontinue ALGOPIRINDOL and contact your doctor or emergency medical services if you notice any of these signs.
BE CAREFUL, because during treatment with all non-steroidal anti-inflammatory drugs (NSAIDs) used for pain and inflammation:

at any time, with or without warning symptoms, and even in patients without prior serious stomach or intestinal (gastrointestinal) problems, bleeding, ulceration, or perforation of the stomach or intestine have been reported, which can be life-threatening (see section "Do not take ALGOPIRINDOL"). If you are elderly or have previously had such problems, your risk of these events increases with higher doses of the medicine. In such cases, your doctor will advise starting treatment with the lowest available dose and may also prescribe a stomach-protecting medicine (gastroprotective agents such as misoprostol or proton pump inhibitors) to be taken alongside ALGOPIRINDOL;
very rarely, serious skin reactions, some of which have been fatal, have been reported, manifesting as redness, blistering, and skin peeling (e.g., exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis). Your risk of such reactions is higher in the early stages of treatment, particularly within the first month;
severe allergic reactions (anaphylactoid reactions) up to anaphylactic shock may occur;
signs of infection may be masked, such as fever, pain, and swelling;
eye problems may occur with ALGOPIRINDOL use. Regular eye examinations are necessary during treatment, especially for prolonged therapy;
headache may occur, especially with prolonged use and high doses. In such cases, do not increase the dose of ALGOPIRINDOL to relieve pain. If you have impaired heart, liver, or kidney function (especially if you have systemic lupus erythematosus), your doctor will prescribe periodic specific tests, particularly for prolonged treatments, and will prescribe the lowest effective dose for the shortest possible duration needed to control symptoms.

The risk of adverse effects can be reduced by using the lowest effective dose for the shortest duration necessary to control symptoms. Do not exceed the recommended dose of ALGOPIRINDOL or take it for long periods; always follow your doctor's instructions carefully.
Stop treatment and inform your doctor in the following cases:

if you experience any unusual abdominal symptoms, especially if they occur at the beginning of treatment. In such cases, the risk of bleeding or ulceration of the digestive tract is higher, particularly if you are elderly, taking high doses of this medicine, or taking other medicines (see section "Other medicines and ALGOPIRINDOL"). If digestive tract bleeding or ulceration occurs, treatment must be stopped as these may be fatal. Exercise particular caution if you have previously had a gastric or intestinal ulcer, especially if it was complicated by perforation or accompanied by bleeding.
if you develop swelling in the legs, heart problems (heart failure), or high blood pressure, which may be symptoms of kidney problems. ALGOPIRINDOL may cause kidney problems, especially in elderly individuals or those with pre-existing kidney, heart, or liver problems, or those taking diuretics or ACE inhibitors. Discontinue treatment if kidney problems occur.
if you develop a skin rash, mucosal lesions, or any other sign of an allergic reaction (e.g., redness, itching, facial or throat swelling, sudden drop in blood pressure).
if you experience vision problems;
if you experience liver problems.

This medicine may cause:

brain problems (aseptic meningitis) in rare cases. This is particularly likely in people suffering from conditions such as systemic lupus erythematosus or related connective tissue diseases.
headache. This is particularly likely with high doses or prolonged treatment.
permanent kidney damage, with risk of kidney failure. This may occur if you habitually take this medicine.
eye problems. If you take this medicine for prolonged periods, undergo regular check-ups.

Heart attack and stroke
Anti-inflammatory/painkillers such as ibuprofen may be associated with a slight increase in the risk of heart attack or stroke, especially when administered at high doses. Do not exceed the recommended dose or treatment duration.
Discuss treatment with your doctor or pharmacist before taking ALGOPIRINDOL if you have:

heart problems including heart attack, angina (chest pain), history of heart attack, coronary bypass surgery, peripheral arterial disease (poor circulation in legs or feet due to narrowed or blocked arteries), or any type of stroke (including "mini-stroke" or "TIA", transient ischemic attack);
high blood pressure, diabetes, high cholesterol, family history of heart disease or stroke, or if you are a smoker.

Infections
ALGOPIRINDOL may mask symptoms of infections such as fever and pain. Therefore, ALGOPIRINDOL may delay appropriate treatment of infection, potentially increasing the risk of complications. This has been observed in bacterial pneumonia and bacterial skin infections associated with chickenpox. If you take this medicine while having an infection and infection symptoms persist or worsen, contact your doctor immediately.
Skin reactions
Serious skin reactions have been reported in association with ALGOPIRINDOL treatment. Stop taking ALGOPIRINDOL and consult your doctor immediately if you develop a skin rash, mucosal lesions, blisters, or other signs of allergy, as these may be early signs of a serious skin reaction. See section 4.
Children
Do not use ALGOPIRINDOL in children under 12 years of age. If necessary, consult your doctor, as lower dosage forms are available for such patients.
Elderly
If you are elderly, you may be more susceptible to adverse effects, particularly bleeding and perforation of the digestive tract, which can be fatal.
Other medicines and ALGOPIRINDOL
Inform your doctor or pharmacist if you are currently taking or have recently taken any other medicines, including over-the-counter medicines.
The side effects of ALGOPIRINDOL may be increased if taken together with certain medicines. ALGOPIRINDOL may also increase or decrease the effects of other medicines or increase their side effects when taken concurrently.
Inform your doctor or pharmacist if you are taking any of the following medicines:

Cox-2 inhibitors and other NSAIDs (e.g., acetylsalicylic acid), medicines used for inflammation;
anticoagulants (used to prevent blood clots), such as aspirin/acetylsalicylic acid, warfarin, or heparin;
platelet aggregation inhibitors (used to prevent blood clots) such as ticlopidine or clopidogrel;
methotrexate (used in the treatment of cancer and autoimmune diseases);
cardiac glycosides, e.g., digoxin (used for treating various heart conditions);
phenytoin (used to prevent epileptic seizures);
lithium (used to treat depression and mania);
diuretics, including potassium-sparing diuretics;
antihypertensives (used to treat high blood pressure) such as:
ACE inhibitors, e.g., captopril
beta-blocker medicines
angiotensin II antagonists;
cholestyramine (used to treat high cholesterol);
aminoglycosides (medicines against certain types of bacteria);
quinolone antibiotics (used for bacterial infections);
SSRIs (medicines for depression) such as paroxetine, sertraline, and citalopram;
moclobemide (RIMA—a medicine used to treat depressive illness or social phobia);
cyclosporine, tacrolimus (used for immunosuppression after organ transplantation);
zidovudine and ritonavir (used in the treatment of HIV-positive patients);
Herbal extracts: Ginkgo Biloba may increase the risk of bleeding when used with NSAIDs;
mifepristone (used for medical abortion);
probenecid or sulfinpyrazone (used to treat gout);
sulfonylureas (used to treat type 2 diabetes);
corticosteroids (used against inflammations);
bisphosphonates (used in osteoporosis, Paget's disease, and to reduce high calcium levels in the blood);
oxpentifylline [(pentoxifylline) used in treating circulatory disease of arteries in legs or arms];
baclofen (a muscle relaxant);
CYP2C9 inhibitors (such as voriconazole and fluconazole) used to treat fungal infections.

ALGOPIRINDOL and alcohol
Avoid drinking alcohol as it may increase the side effects of ALGOPIRINDOL, particularly those affecting the stomach, intestine, or brain.
Pregnancy, breastfeeding, and fertility
If you are pregnant, suspect you may be pregnant, planning a pregnancy, or breastfeeding, consult your doctor or pharmacist before taking this medicine.
Pregnancy
Do not take ibuprofen during the last three months of pregnancy, as it may harm the fetus or cause problems during childbirth.
It may cause kidney and heart problems in the fetus. It may affect your and your baby's tendency to bleed and may delay or prolong labour beyond normal. You should not take ibuprofen during the first six months of pregnancy unless absolutely necessary and under medical advice. If treatment is required during this period or during attempts to conceive, the lowest possible dose for the shortest possible time should be used. From week 20 of pregnancy, ibuprofen may cause kidney problems in the fetus if taken for more than a few days, reducing the levels of amniotic fluid surrounding the baby (oligohydramnios), or cause narrowing of a blood vessel (ductus arteriosus) in the baby's heart. If treatment is required for more than a few days, your doctor may recommend additional monitoring.
Breastfeeding
ALGOPIRINDOL passes into breast milk in very small amounts and it is generally not necessary to stop breastfeeding during short-term treatment. However, if prolonged treatment is prescribed, your doctor may consider early weaning.
Fertility
ALGOPIRINDOL may reduce the likelihood of becoming pregnant. Inform your doctor if you are planning a pregnancy or have fertility problems.
Driving and using machines
ALGOPIRINDOL may cause side effects that can impair your reaction time, such as headache, fatigue, drowsiness, dizziness, vertigo, and vision disturbances. Make sure you do not experience any of these side effects before driving, operating machinery, or doing anything that requires alertness. This is particularly important if you consume alcohol during ALGOPIRINDOL treatment.
ALGOPIRINDOL contains lactose
This medicine contains lactose. If your doctor has diagnosed you with an intolerance to certain sugars, contact them before taking this medicine.
ALGOPIRINDOL contains sodium
This medicine contains less than 1 mmol (23 mg) of sodium per tablet, i.e., essentially 'sodium-free'.

3. How to take ALGOPIRINDOL

Take this medicine exactly as directed by your doctor or pharmacist. If you have
any doubts, consult your doctor or pharmacist.
The lowest effective dose for the shortest duration necessary to relieve symptoms should be used.
If you have an infection, contact your doctor immediately if symptoms (such as fever and
pain) persist or worsen (see section 2).
Undesirable effects can be minimized by using the lowest effective dose for the shortest duration needed to control symptoms.
The dose of ALGOPIRINDOL depends on the patient's age and body weight. The usual dose is:
Adults
The recommended dose is 600 mg three times daily. Do not exceed the maximum daily dose of 1800 mg. Your doctor
may prescribe lower doses. Depending on your condition, your doctor may increase the dose up to a maximum of 2400 mg per day, divided into 3 or 4 doses.
Use in adolescents over 12 years of age
These tablets may not be suitable for patients in this age group and body weight range, as one tablet of ALGOPIRINDOL may contain a level of active substance higher than appropriate. Your doctor will advise you accordingly.
Use in patients with kidney or liver problems
If you have kidney or liver problems, your doctor will determine the most appropriate dose for you, possibly reducing the doses indicated above. If you have severe kidney or liver problems, you must not take this medicine (see "Do not take ALGOPIRINDOL").
Use in the elderly
Your doctor will determine the necessary dose in these cases. If you are elderly, you are more likely to experience adverse effects, particularly gastrointestinal bleeding and perforation, which may be fatal.
If you take more ALGOPIRINDOL than you should
If you have taken more ALGOPIRINDOL than you should, or if your child has accidentally taken this medicine,
contact a doctor or the nearest hospital immediately to obtain advice on the risk and actions to be taken.
Symptoms of overdose may include nausea, stomach ache, vomiting (possibly with traces of blood), headache, tinnitus, confusion, and uncontrolled eye movements.
At high doses, drowsiness, chest pain, palpitations, loss of consciousness, seizures (especially in children), weakness, dizziness, blood in the urine, low blood potassium levels, feeling cold, and breathing difficulties may occur.
Rarely, uncontrolled eye movements (nystagmus), increased levels of acid in the blood (metabolic acidosis), reduced body temperature (hypothermia), kidney impairment, gastrointestinal bleeding, coma, temporary cessation of breathing (apnea), diarrhoea, reduced activity of the central nervous system and respiratory depression may occur.
In addition, disorientation, agitation, fainting, low blood pressure (hypotension), decreased or increased heart rate (bradycardia or tachycardia), and lethargy may occur.
In cases of severe poisoning, prolonged blood clotting time (prolonged prothrombin time (INR)) may occur.
If you suffer from asthma, your symptoms may worsen.
If you take significantly excessive doses, you may experience severe kidney and liver damage.
Symptoms of overdose may appear within 4–6 hours after taking ibuprofen.
In case of accidental ingestion or overdose of ALGOPIRINDOL, contact your doctor immediately or go to the nearest hospital.
If you have any doubts about the use of ALGOPIRINDOL, consult your doctor or pharmacist.
If you forget to take ALGOPIRINDOL
If you forget to take a dose, take it as soon as possible, unless it is less than 4 hours before the next dose. Do not take a double dose to make up for the missed dose.
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone will experience them.
Side effects are more likely with higher doses and longer duration of treatment.
Medicines such as ALGOPIRINDOL may be associated with a slightly increased risk of heart attack (myocardial infarction) or stroke. Fluid retention (edema), high blood pressure, and heart problems (heart failure) have been reported in association with NSAIDs.

Serious side effects
Stop treatment with ALGOPIRINDOL and contact your doctor immediately if you experience any of the following side effects:

severe stomach problems, burning or abdominal pain due to injury of the stomach or intestine (peptic ulcers), sudden and severe pain in the upper abdomen or stomach area (gastrointestinal perforation). These side effects are uncommon;
vomiting blood (haematemesis) or black stools (melena), bleeding from the stomach or intestine (gastrointestinal haemorrhage). These conditions are common side effects;
allergic reactions, even severe ones, presenting as more or less sudden appearance of skin lesions, such as widespread redness or spots (rash, purpura), hives, itching, swelling of the face, eyes, lips, angioedema of the throat with possible difficulty in breathing and swallowing. These conditions occur with uncommon frequency. Rarely, a severe, potentially life-threatening allergic reaction may occur, characterized by increased heart rate and sudden drop in blood pressure (anaphylactic reactions, anaphylaxis);
difficulty in breathing (asthma, even severe, bronchospasm or dyspnea, apnea). These conditions are uncommon side effects;
systemic lupus erythematosus (SLE), a disease affecting connective tissue causing joint or muscle pain, skin changes, and problems in other organs. This condition occurs rarely;
worsening of infections, such as the onset of necrotizing fasciitis, presenting with fever, chills, weakness, sweating, diarrhoea, vomiting, redness, pain, swelling, bruising in an area of the body due to tissue necrosis (death of tissue cells);
inflammation of the meninges (aseptic meningitis), presenting with: high fever, sudden headache, inability to bend the neck, nausea, vomiting, confusion, drowsiness, and sensitivity to light. This condition occurs rarely;
flat, red, target-shaped or circular spots on the trunk, often with central blisters, skin peeling, mouth, throat, nose, genital, and eye ulcers. These severe skin rashes may be preceded by fever and flu-like symptoms [exfoliative and bullous dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis];
widespread skin rash, high body temperature, swollen lymph nodes, and increased eosinophils (a type of white blood cells) (DRESS syndrome);
widespread, red, scaly rash with bumps under the skin and blisters, accompanied by fever. Symptoms usually occur at the beginning of treatment (generalized pustular eruption).

Other side effects
Inform your doctor if you notice:
Common side effects (may affect up to 1 in 10 people):

indigestion (dyspepsia), diarrhoea, nausea, vomiting, abdominal pain, intestinal gas (flatulence), constipation
headache, dizziness, vertigo, fatigue, restlessness, irritability

Uncommon side effects (may affect up to 1 in 100 people)

skin becomes sensitive to light,
inflammation of the nose (rhinitis);
inflammation of the stomach (gastritis), mouth ulcers;
dizziness, drowsiness, difficulty falling asleep (insomnia), anxiety, changes in sensation (paraesthesia);
impaired hearing, ringing in the ears (tinnitus), vision disturbances;
skin reactions following exposure to sunlight (photosensitivity);
changes in liver function, yellowing of the eyes or skin (jaundice), dark urine, pale stools, itching or abdominal pain, inflammation of the liver (hepatitis);
kidney problems such as nephrotic syndrome, inflammation of the kidney (tubulointerstitial nephritis), changes in function (renal failure), development of edema.

Rare side effects (may affect up to 1 in 1,000 people)

decrease in the number of white blood cells (leucopenia) or of certain types of white blood cells (neutropenia, agranulocytosis), decrease in the number of platelets (thrombocytopenia), decrease in all blood cells, decrease in red blood cells due to destruction (haemolytic anaemia) or due to bone marrow problems (aplastic anaemia);
depression, confusion;
changes in vision, for example due to inflammation of the optic nerve (optic neuritis) or toxic optic neuropathy;
swelling (edema);
increased blood urea nitrogen and liver enzymes, decreased haemoglobin and haematocrit, inhibition of platelet aggregation and prolonged bleeding time, decreased calcium and increased serum uric acid.

Very rare side effects (may affect up to 1 in 10,000 people)

reduced liver function, inflammation of the oesophagus or pancreas (pancreatitis);
intestinal narrowing
sensation of the heart pounding (palpitations), heart attack (myocardial infarction), reduced heart function (heart failure), high blood pressure (hypertension);
breathing problems due to pulmonary edema;
hair loss (alopecia).

Side effects with unknown frequency (frequency cannot be estimated from the available data):

a widespread, red, scaly rash, with pustules forming under the skin and blisters, mainly localized in skin folds, trunk, and upper limbs, accompanied by fever at the beginning of treatment (generalized pustular eruption). Stop using ALGOPIRINDOL if you develop these symptoms and contact your doctor immediately. See also section 2.
chest pain, which may be a sign of a potentially severe allergic reaction called Kounis syndrome.

Other side effects

pain or burning (pyrosis) in the upper stomach, inflammation of the mouth mucosa with ulcers (ulcerative stomatitis);
worsening of inflammation of the colon (colitis) or Crohn's disease, and complications of diverticula of the large intestine (perforation or fistula);
worsening of skin infections caused by chickenpox;
stroke;
hallucinations, malaise.

ALGOPIRINDOL may cause a reduction in the number of white blood cells and decrease your resistance to infections. If you develop an infection with symptoms such as fever and severe worsening of general health, or fever with signs of localized infection such as sore throat/pharynx/mouth or urinary problems, contact your doctor immediately. In this case, you will need a blood test to determine any reduction in white blood cells (agranulocytosis). Inform your doctor that you are taking this medicine.
During treatment with ALGOPIRINDOL, meningitis (with signs such as neck stiffness, headache, nausea, vomiting, fever, or disorientation) may occur in people with pre-existing immune system disorders, such as systemic lupus erythematosus or mixed connective tissue disease.

Reporting of side effects
If you experience any side effect, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse. By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store ALGOPIRINDOL

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the pack after "Exp.". The expiry date refers to the last day of the month.
This medicine does not require any special storage conditions.
Do not dispose of medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use. This will help protect the environment.

6. Package contents and other information

What ALGOPIRINDOL contains

The active substance is ibuprofen. Each film-coated tablet contains 600 mg of ibuprofen.
The other components are: Core: microcrystalline cellulose, sodium croscarmellose, sodium lauryl sulfate, hypromellose, monohydrate lactose, talc, anhydrous colloidal silica, glycerol dibehenate. Coating: hypromellose, monohydrate lactose, triacetin, titanium dioxide.

Description of the appearance of ALGOPIRINDOL and package contents
600 mg film-coated tablets – 30 tablets
Marketing Authorization Holder
So.Se.PHARM S.r.l. – Via dei Castelli Romani 22, 00071 Pomezia (RM) - Italy
Manufacturer
Special Product’s Line S.p.a.
Via Fratta Rotonda Vado Largo, 1
03012 Anagni (FR), Italy

Algopirindol