Fungarest 20 mg/g cream

Spain
Brand name Fungarest 20 mg/g cream
Form cream
Active substance / Dosage
Prescription type Prescription Only Medicine
Registration number 57595
Fungarest 20 mg/g cream cream

Package leaflet: Information for the user

Introduction

Package leaflet: information for the user

FUNGAREST 20 mg/g cream

ketoconazole

Read the entire leaflet carefully before you start using this medicine, because it contains important information for you.

  • Keep this leaflet, as you may need to read it again.

  • If you have any questions, ask your doctor or pharmacist.

  • This medicine has been prescribed for you only, and you should not give it to other people, even if they have the same symptoms as you, because it may harm them.

  • If you experience any adverse effects, consult your doctor or pharmacist, even if they are adverse effects not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What Fungarest is and what it is used for

  2. What you need to know before using Fungarest

  3. How to use Fungarest

  4. Possible side effects

  5. How to store Fungarest

  6. Contents of the pack and other information

1. What Fungarest is and what it is used for

Ketoconazole belongs to a group of medicines called antifungals (medicines used to treat infections caused by fungi and yeasts).

This medicine is indicated in adults for the treatment of the following superficial skin infections:

  • Cutaneous candidiasis, infections that usually affect warm, moist areas of the skin and mucous membranes.

  • Pityriasis versicolor, a condition characterized by discolored patches appearing on the skin.

  • Seborrheic dermatitis, a condition affecting mainly the face and chest, causing redness and flaking of the skin.

  • Tinea infections, a condition that may affect the trunk (tinea corporis), groin (tinea cruris), feet (tinea pedis), and hands (tinea manuum).

2. What you need to know before using Fungarest

Do not use Fungarest

  • If you are allergic to ketoconazole or to any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor or pharmacist before starting to use Fungarest.

For external use only. Contact with the eyes should be avoided. If accidental contact with the eyes occurs, wash thoroughly with plenty of water and consult an ophthalmologist if necessary.

If you are using corticosteroid creams, ointments, or lotions, inform your doctor or pharmacist before starting treatment with this medicine. You may begin treatment with this medicine, but you should not stop applying the corticosteroid abruptly. The skin may react, resulting in redness or itching. Continue your treatment as follows:

  • apply a mild corticosteroid to the skin in the morning and Fungarest cream in the evening for one week;
  • subsequently, apply the corticosteroid in the morning every two or three days, and Fungarest cream in the evenings for 1 to 2 weeks;
  • then completely discontinue the corticosteroid and, if necessary, continue treatment with this medicine alone.

If an allergic reaction occurs, wash the cream off the skin, stop treatment immediately, and consult your doctor without delay.

Children and adolescents

The safety and efficacy of ketoconazole cream in children and adolescents have not been established.

Other medicines and Fungarest

Inform your doctor or pharmacist if you are taking, have recently taken, or might need to take any other medicines.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to become pregnant, consult your doctor or pharmacist before using this medicine.

As a precautionary measure, it is preferable to avoid using this medicine during pregnancy and breastfeeding.

Driving and using machines

Given the characteristics of this medicine, no effect on driving or operating machinery is expected.

Fungarest contains propylene glycol, cetyl alcohol, and stearyl alcohol

This medicine contains 200 mg of propylene glycol per gram.

Propylene glycol may cause skin irritation.

This medicine contains propylene glycol; do not use on open wounds or large areas of damaged skin (such as burns) without consulting your doctor or pharmacist first.

This medicine may cause local skin reactions (such as contact dermatitis) because it contains cetyl alcohol and stearyl alcohol.

3. How to use Fungarest

Follow exactly the instructions for use of this medicine as given by your doctor. If in doubt, consult your doctor or pharmacist again.

This medicine should be applied once or twice daily, depending on the type of infection.

The recommended dosage is:

  • Cutaneous candidiasis: 2 to 3 weeks
  • Pityriasis versicolor: 2 to 3 weeks
  • Tinea corporis (ringworm of the body): 3-4 weeks
  • Tinea cruris (jock itch): 2-4 weeks
  • Tinea pedis (athlete's foot): 4-6 weeks
  • Tinea manuum (ringworm of the hands): your doctor will advise you on how and for how long this medicine should be applied.

For skin infections presenting with reddish-brown patches and yellow or white scaling (seborrheic dermatitis), apply Fungarest cream once or twice daily. Skin infections usually improve within 2 to 4 weeks.

You will usually notice signs of improvement after 4 weeks. If this is not the case, speak with your doctor.

Continue using the cream for a few days after all symptoms have disappeared.

Sometimes it is necessary to apply the cream once a week or once every two weeks, even after the skin has completely healed. This helps prevent symptoms from recurring.

Elderly patients

There are no specific dosage recommendations for these patients.

Method of administration

For topical use only.

Wash and dry the infected skin area before applying the medicine. Gently rub the cream into the skin using the fingertips. Do not treat only the visibly infected area; also apply the cream to the surrounding skin. Wash your hands thoroughly after applying the cream (this is important to prevent spreading the infection to other parts of the body or to other people).

To open the tube, unscrew the cap and use the top of the cap to pierce the seal of the tube.

If you use more Fungarest than you should

If more Fungarest is applied than your doctor has recommended, you may experience a burning sensation, redness, or swelling, which will disappear once treatment is discontinued.

This medicine must not be ingested. If accidentally swallowed, contact your doctor.

In case of overdose or accidental ingestion, contact your doctor or pharmacist immediately, or call the Toxicology Information Service at telephone number: 91 562 04 20, stating the medicine and the amount taken.

If you forget to use Fungarest

Do not apply a double dose to make up for missed doses.

If you stop using Fungarest

Do not stop treatment without consulting your doctor, as symptoms of your condition may return or worsen.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible adverse effects

Like all medicines, this medicine may cause adverse effects, although not everyone experiences them.

Frequent adverse effects (may affect up to 1 in 10 people)

  • Sensation of burning on the skin.
  • Redness of the skin at the application site.
  • Itching at the site of administration.

Uncommon adverse effects (may affect up to 1 in 100 people)

  • Allergic reactions (hypersensitivity).
  • Localized eczema (contact dermatitis).
  • Skin rash.
  • Skin eruption.
  • Skin peeling (desquamation).
  • Oily, sticky skin.
  • Other reactions at the administration site: bleeding, discomfort, dryness, swelling, irritation, paresthesia (tingling, numbness).

Adverse effects of unknown frequency (cannot be estimated from available data)

  • Urticaria.

Reporting of adverse effects

If you experience any type of adverse effect, consult your doctor or pharmacist, even if it involves possible adverse effects not listed in this leaflet. You may also report them directly through the Spanish Pharmacovigilance System for Human Medicines: https://www.notificaram.es. By reporting adverse effects, you can help provide more information on the safety of this medicine.

5. Storage of Fungarest

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton and tube after EXP. The expiry date refers to the last day of the month indicated.

No special storage conditions are required.

Dispose of the container once treatment has ended.

Do not use this medicine if you notice any signs of deterioration.

Medicines must not be disposed of via wastewater or household waste. Return unused containers and unwanted medicines to the SIGRE point at your pharmacy. If you are in doubt, please ask your pharmacist how to dispose of medicines and containers you no longer need. This will help protect the environment.

6. Contents of the pack and other information

Composition of Fungarest

The active substance is ketoconazole. Each gram of cream contains 20 mg of ketoconazole.

The other components (excipients) are:

  • propylene glycol (E-1520),
  • stearyl alcohol,
  • cetyl alcohol,
  • sorbitan monostearate,
  • polysorbate 60,
  • polysorbate 80,
  • isopropyl myristate,
  • sodium sulfite (E-221), and
  • purified water.

Appearance of the product and contents of the pack

White, homogeneous cream.

This medicine is available in 30-gram tubes.

Marketing Authorization Holder

Laboratorio STADA, S.L.
Frederic Mompou, 5
08960 Sant Just Desvern (Barcelona)
Spain

Manufacturer

JANSSEN PHARMACEUTICA, N.V.
Turnhoutseweg, 30
2340 Beerse (Belgium)

or

STADA Arzneimittel AG
Stadastrasse 2-18
61118 Bad Vilbel
Germany

Date of the most recent revision of this leaflet: June 2021

Other sources of information

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency of Medicines and Health Products (AEMPS) (http://www.aemps.gob.es).