Streptocide

INSTRUCTIONS FOR MEDICAL USE OF THE DRUG STREPTOCID

Composition:

1 g of liniment contains:

Active substance: sulfanilamide (streptocid) - 50 mg;

Excipients: purified fish oil for external use, butylhydroxyanisole (E 320), emulsifier No. 1, polysorbate-80 or purified sodium carboxymethylcellulose, purified water;

Excipients included in emulsifier No. 1: cetyl alcohol, stearyl alcohol.

Pharmaceutical form. Liniment.

Main physicochemical properties: liniment of white color with yellowish or yellowish-brownish tint, with a specific odor.

Pharmacotherapeutic group.

Chemotherapeutic agents for topical use. Sulfonamides. ATC code D06B A05.

Pharmacological properties.

Pharmacodynamics.

The drug exhibits antimicrobial activity against streptococci and other microorganisms. Streptocide disrupts the assimilation process in microbial cells of growth factors – folic acid, dihydrofolic acid, and other compounds containing para-aminobenzoic acid (PABA). Due to the similarity in chemical structure between PABA and sulfanilamide, the latter acts as a competitive antagonist of the acid, incorporates into microbial metabolism, and disrupts it.

Pharmacokinetics.

Not studied.

Clinical characteristics.

Indications.

Ulcers, burns, fissures, wounds, pyoderma, skin ulcers, purulent-inflammatory skin conditions not accompanied by pronounced exudation, infected wounds in the regeneration phase.

Contraindications.

Hypersensitivity to the components of the drug or to any other sulfonamide agents. Renal failure, acute porphyria. Pregnancy or breastfeeding period.

Special precautions.

If an allergic reaction occurs at the site of liniment application, the use of the drug should be discontinued.

Premature discontinuation of treatment with the drug may lead to the development of sulfonamide-resistant microorganisms.

Interaction with other medicinal products and other types of interactions.

During the use of Streptocid, it is undesirable to take the following drugs: digoxin, hydrochloric acid, caffeine, mesaton, phenobarbital, adrenaline hydrochloride.

Novocaine, which contains a para-aminobenzoic acid residue, reduces the effectiveness of the drug if these medicinal agents are used consecutively.

Instructions for use.

Use during pregnancy or breastfeeding.

Not recommended.

Ability to affect reaction speed when driving or operating machinery.

No effect.

Method of administration and dosage.

The liniment should be applied in a thin layer to the affected area, including under a gauze dressing. Frequency and duration of use depend on the severity of the disease, the therapeutic effect achieved, and are determined individually by a physician.

Children.

Safety and efficacy of Streptocide in children have not been established; therefore, the drug should not be prescribed to patients in this age group.

Overdose.

In case of overdose, adverse drug reactions may become more pronounced.

Treatment: symptomatic therapy.

Adverse reactions.

Local allergic reactions (including dermatitis, urticaria) may occur in cases of hypersensitivity to sulfonamide agents; if such reactions develop, the drug must be discontinued immediately.

Shelf life. 2 years.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C.

Freezing is not permitted.

Keep out of reach of children.

After opening the tube, the preparation should be stored throughout the course of treatment.

Packaging. 30 g in tubes, 1 tube per package.

Prescription status. Over-the-counter.

Manufacturer. JSC "Lubnyfarm".

Manufacturer's address and location of business activity.

16, Barvinkova St., Lubny, Poltava region, 37500, Ukraine.

INSTRUCTION

for medical use of the drug

STREPTOCID

Composition:

1 g of liniment contains:

Active ingredient: sulfanilamide (streptocid) 50 mg;

Excipients: purified fish oil for external use, butylated hydroxyanisole (E 320), emulsifier No. 1, polysorbate-80 or purified sodium carboxymethylcellulose, purified water;

Excipients contained in emulsifier No. 1: cetyl alcohol, stearyl alcohol.

Pharmaceutical form. Liniment.

Main physicochemical properties: a white liniment with a yellowish or yellowish-brown tint, with a specific odor.

Pharmacotherapeutic group.

Chemotherapeutic agents for topical use. Sulfonamides. ATC code D06B A05.

Pharmacological properties.

Pharmacodynamics.

The drug exerts antimicrobial activity against streptococci and other microorganisms. Streptocid disrupts the assimilation process in microbial cells of growth factors—folic acid, dihydrofolic acid, and other compounds containing para-aminobenzoic acid (PABA). Due to the similarity in chemical structure between PABA and sulfanilamide, the latter acts as a competitive antagonist of the acid, incorporates into microbial metabolism, and disrupts it.

Pharmacokinetics.

Not studied.

Clinical characteristics.

Indications.

Ulcers, burns, fissures, wounds, pyoderma, erysipelas of the skin, purulent-inflammatory skin conditions without pronounced exudation, infected wounds in the regeneration phase.

Contraindications.

Hypersensitivity to the components of the drug or to any other sulfonamide agents. Renal failure, acute porphyria. Pregnancy or breastfeeding period.

Special precautions.

If an allergic reaction occurs at the site of liniment application, discontinue use of the drug.

Premature discontinuation of treatment may lead to the development of sulfonamide-resistant microorganisms.

Interaction with other medicinal products and other types of interactions.

During the use of Streptocid, concomitant use of digoxin, hydrochloric acid, caffeine, mesaton (phenylephrine), phenobarbital, or adrenaline hydrochloride is not recommended.

Procaine, which contains a para-aminobenzoic acid residue, reduces the efficacy of the drug when both agents are used consecutively.

Special instructions.

Use during pregnancy or breastfeeding.

Not recommended.

Ability to affect reaction rate while driving or operating machinery.

Does not affect.

Method of administration and dosage.

Apply the liniment in a thin layer to the affected area, including under a gauze dressing. Frequency and duration of use depend on the severity of the condition and the therapeutic effect achieved, and are determined individually by a physician.

Children.

The safety and efficacy of Streptocid in children have not been established; therefore, the drug should not be prescribed to this age group.

Overdose.

Overdose may lead to an increase in the drug's adverse effects.

Treatment: symptomatic therapy.

Adverse reactions.

Local allergic reactions (including dermatitis, urticaria) may occur in cases of hypersensitivity to sulfonamide agents; if such reactions develop, the drug must be discontinued immediately.

Shelf life. 2 years.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C.

Freezing is not permitted.

Keep out of reach of children.

After opening the tube, the preparation should be stored throughout the course of treatment.

Packaging. 30 g in tubes, 1 tube per package.

Prescription status. Over-the-counter.

Manufacturer. JSC "Lubnyfarm".

Manufacturer's address and location of business activity.

16, Barvinkova St., Lubny, Poltava region, 37500, Ukraine.