Nephrofit

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT NEPHROFIT

Composition:

Active ingredients: 1 package (50 g) contains a mixture of herbal raw materials: elder flowers (Sambuci flos) 4.5 g, greater plantain leaves (Plantaginis majoris folium) 4.5 g, knotweed herb (Polygoni avicularis herba) 4.5 g, horsetail herb (Equiseti herba) 4.5 g, shepherd's purse herb (Bursae pastoris herba) 4 g, corn stigmas with styles (Zeae maydis styli cum stigmatis) 4 g, dandelion roots (Taraxaci officinalis radix) 4 g, burdock roots (Arctii radix) 4 g, bearberry leaves (Uvae ursi folium) 4 g, peppermint leaves (Menthae piperitae folium) 4 g, chamomile flowers (Matricariae flos) 4 g, bidens herb (Bidentis herba) 4 g.

Pharmaceutical form. Herbal mixture.

Main physicochemical properties: a mixture of fragments of various shapes, grayish-green in color, with reddish-brown, yellow and white inclusions. Odor is strong and pleasant.

Pharmacotherapeutic group. Agents used in urology. ATC code G04BX.

Pharmacological Properties.

Pharmacodynamics.

NEPHROFIT exhibits diuretic action and enhances the kidney's nitrogen excretion function. It has a mild saluretic effect, i.e. promotes moderate excretion of salts. It positively influences hepatic urine formation and renal clearance function. It has spasmolytic, anti-inflammatory, and antibacterial effects.

Clinical characteristics.

Indications. Complex treatment and prevention of exacerbations of inflammatory diseases of the kidneys and urinary tract accompanied by reduced urinary and nitrogen excretory function, urolithiasis, edema.

Contraindications. Gastropathy with increased secretion, chronic renal failure, peptic ulcer of the stomach in the stage of exacerbation, obstructive jaundice, cholelithiasis with presence of stones over 10 mm in diameter, acute cholecystitis, acute hepatitis, liver cirrhosis, obstruction of biliary tract, thrombophlebitis, diphtheria, anorexia; hypersensitivity to any component of the drug.

Special precautions. Should be used with caution in patients with increased blood coagulability, bronchial asthma, spasmophilia, and in patients with gastroesophageal reflux (heartburn).

Interaction with other medicinal products and other types of interactions. Do not use simultaneously with medicinal products and food that reduce urine pH. Antacids and H2-blockers reduce the effectiveness of the drug.

Special precautions for use.

Use during pregnancy or breastfeeding. Possible increase in uterine tone. Due to insufficient experience with the use of the drug during pregnancy, it should be used during pregnancy only if prescribed by a physician and when the expected benefit for the mother outweighs the potential risk to fetal development. If it is necessary to use the medicinal product, breastfeeding should be discontinued.

Ability to influence reaction rate when driving or operating machinery. No effect.

Method of Administration and Dosage.

Steep 2 tablespoons of the herbal mixture in 500 ml of boiling water, let stand in a closed container for 1 hour, then strain.

For adults and children aged 7 years and older, take ⅔ cup (150 ml) of the warm preparation 20–30 minutes before meals, 3 times daily.

The duration of treatment is determined by a physician. Typically, the treatment course lasts up to 2 months. If necessary, the course may be repeated upon physician's recommendation with an interval of 3–4 weeks.

Children. The preparation is contraindicated for children under 7 years of age.

Overdose. Symptoms of dyspepsia and increased incidence of adverse reactions may occur.

Adverse reactions.

The medicinal product is generally well tolerated by patients. However, due to its multi-component composition, allergic reactions are possible, primarily in cases of individual hypersensitivity to any of the components or in violation of the recommended regimen. Such reactions may include hyperemia, rash, pruritus, angioneurotic edema, contact dermatitis, and urticaria. Leaves of Urtica dioica (nettle) may cause pain in the lumbar region, changes in urine color, and discomfort at the end of urination. Although NEPHROFIT contains only a small amount of nettle leaves, such symptoms cannot be completely excluded.

In the event of any adverse reactions, consult a physician immediately.

Shelf life. 2 years. Do not use after the expiry date stated on the package.

Storage conditions. In the original packaging, at a temperature not exceeding 25 °C, in a place inaccessible to children.

Packaging. 50 g per packet, placed in a carton.

Availability. Over-the-counter (without prescription).

Manufacturer. LLC "Scientific-Production Pharmaceutical Company "EYM".

Manufacturer's address. A-5, 20 Kharkivs'kykh Dyviziy Street, Kharkiv, Kharkiv region, 61091, Ukraine.

INSTRUCTION

for medical use of the medicinal product

NEPHROFIT

Composition:

Active substances: 1 pack (100 g) contains a mixture of medicinal plant raw materials: elder flowers (Sambuci flos) 9 g, greater plantain leaves (Plantaginis majoris folium) 9 g, knotweed herb (Polygoni avicularis herba) 9 g, horsetail herb (Equiseti herba) 9 g, common shepherd's purse herb (Bursae pastoris herba) 8 g, corn silk with stigmas (Zeae maydis styli cum stigmatis) 8 g, dandelion roots (Taraxaci officinalis radix) 8 g, burdock roots (Arctii radix) 8 g, bearberry leaves (Uvae ursi folium) 8 g, peppermint leaves (Menthae piperitae folium) 8 g, chamomile flowers (Matricariae flos) 8 g, bidens herb (Bidentis herba) 8 g.

Pharmaceutical form. Herbal mixture.

Main physico-chemical characteristics: a mixture of irregularly shaped fragments of greyish-green color with brownish-red, yellow and white inclusions. Odor strong, pleasant.

Pharmacotherapeutic group. Medicinal products used in urology. ATC code G04BX.

Pharmacological properties.

Pharmacodynamics.

NEPHROFIT exhibits diuretic action and enhances renal nitrogen excretion function, has mild saluretic effect, i.e. promotes moderate excretion of salts. Exerts positive effect on hepatic urea formation function and renal clearance function. Has spasmolytic, anti-inflammatory and antibacterial actions.

Clinical characteristics.

Indications. Complex treatment and prevention of exacerbations of inflammatory diseases of the kidneys and urinary tract accompanied by reduced urinary and nitrogen excretory function, urolithiasis, edema.

Contraindications. Gastropathy with increased secretion, chronic renal failure, peptic ulcer disease in the stage of exacerbation, obstructive jaundice, cholelithiasis with presence of stones over 10 mm in diameter, acute cholecystitis, acute hepatitis, liver cirrhosis, biliary tract obstruction, thrombophlebitis, lobar pneumonia, anorexia; hypersensitivity to any component of the drug.

Special precautions. Should be used with caution in patients with increased blood coagulability, bronchial asthma, spasmophilia, and also in patients with gastroesophageal reflux (heartburn).

Interaction with other medicinal products and other types of interactions. Do not use simultaneously with medicinal products and food that reduce urine pH. Antacids and H2-blockers reduce the effectiveness of the drug.

Special precautions for use.

Use during pregnancy or breastfeeding. Possible increase in uterine tone. Due to the lack of sufficient experience with the use of the drug during pregnancy, it should be used during pregnancy only if prescribed by a physician, when the expected benefit for the mother outweighs the potential risk to fetal development. If it is necessary to use the drug, breastfeeding should be discontinued.

Ability to affect reaction speed when driving or operating machinery. No effect.

Method of Administration and Dosage.

Steep 2 tablespoons of the herbal mixture in 500 ml of boiling water, leave covered for 1 hour, then strain.

For adults and children aged 7 years and older, take ⅔ cup (150 ml) of the warm preparation 20–30 minutes before meals, 3 times daily.

The duration of use should be determined by a physician. Typically, the treatment course lasts up to 2 months. If necessary, the treatment course may be repeated as prescribed by a doctor, with an interval of 3–4 weeks.

Children. The preparation is contraindicated in children under 7 years of age.

Overdose. Possible occurrence of dyspeptic symptoms and increased intensity of adverse reactions.

Adverse reactions.

The medicinal product is generally well tolerated by patients. However, due to its multi-component composition, allergic reactions are possible, mostly in cases of individual hypersensitivity to any of the components or in case of violation of the recommended dosage regimen. Such reactions may include hyperemia, rash, itching, angioneurotic edema, contact dermatitis, and urticaria. Nettle leaves may cause pain in the lumbar region, changes in urine color, as well as pain at the end of urination. Although NEFROFIT herbal blend contains only a small amount of nettle leaves, such symptoms cannot be completely excluded.

In case of any adverse reactions, consult a physician immediately.

Shelf life. 2 years. Do not use after the expiry date stated on the package.

Storage conditions. In the original packaging, at a temperature not exceeding 25 °C, in a place inaccessible to children.

Packaging. 100 g per packet, placed in a carton.

Availability. Over-the-counter (without prescription).

Manufacturer. LLC "Scientific-Production Pharmaceutical Company "EYM".

Manufacturer's address. 20 lit. "A-5", Kharkivs'kykh Dyviziï Street, Kharkiv, Kharkiv region, 61091, Ukraine.

INSTRUCTION

for medical use of the medicinal product

NEFROFIT

Composition:

Active substances: 1 filter bag (1.5 g) contains a mixture of herbal raw materials: elder flowers (Sambuci flos) 135 mg, plantain leaf (Plantaginis majoris folium) 135 mg, knotweed herb (Polygoni avicularis herba) 135 mg, horsetail herb (Equiseti herba) 135 mg, shepherd's purse herb (Bursae pastoris herba) 120 mg, corn stigmas and styles (Zeae maydis styli cum stigmatis) 120 mg, dandelion root (Taraxaci officinalis radix) 120 mg, burdock root (Arctii radix) 120 mg, bearberry leaf (Uvae ursi folium) 120 mg, peppermint leaf (Menthae piperitae folium) 120 mg, chamomile flowers (Matricariae flos) 120 mg, and beggarticks herb (Bidentis herba) 120 mg.

Pharmaceutical form. Herbal mixture.

Main physicochemical properties: a mixture of irregularly shaped fragments of grayish-green color with reddish-brown, yellow, and white inclusions. Odor is strong and pleasant.

Pharmacotherapeutic group. Medicinal products used in urology. ATC Code: G04BX.

Pharmacological properties.

Pharmacodynamics.

NEFROFIT exhibits diuretic action and enhances renal nitrogen excretion function, has mild saluretic effect, i.e. promotes moderate elimination of salts. It positively influences hepatic urea formation function and renal clearance function. It has spasmolytic, anti-inflammatory, and antibacterial effects.

Clinical characteristics.

Indications. Complex treatment and prevention of exacerbations of inflammatory diseases of the kidneys and urinary tract accompanied by reduced urinary and nitrogen excretory function, urolithiasis, edema.

Contraindications. Gastropathy with increased secretion, chronic renal failure, peptic ulcer disease in the stage of exacerbation, obstructive jaundice, cholelithiasis with presence of stones over 10 mm in diameter, acute cholecystitis, acute hepatitis, liver cirrhosis, biliary tract obstruction, thrombophlebitis, diphtheria, anorexia; hypersensitivity to any component of the drug.

Special precautions. Should be used with caution in patients with increased blood coagulation, bronchial asthma, spasmophilia, and in patients with gastroesophageal reflux (heartburn).

Interaction with other medicinal products and other forms of interaction. Do not use simultaneously with medicinal products and food that reduce urine pH. Antacids and H2-blockers reduce the drug's effectiveness.

Special precautions.

Use during pregnancy or breastfeeding. Possible increase in uterine tone. Due to the lack of sufficient experience with the use of the drug during pregnancy, it should be used only under a physician's supervision when the expected benefit to the mother outweighs the potential risk to fetal development. If treatment with the medicinal product is necessary, breastfeeding should be discontinued.

Ability to affect reaction speed when driving or operating machinery. No effect.

Method of administration and dosage.

Pour 150 ml of boiling water over 2 filter bags, let stand in a closed container for 15 minutes.

For adults and children aged 7 years and older, take 150 ml of the warm preparation 20–30 minutes before meals, three times daily.

The duration of use should be determined by a physician. Usually, the treatment course lasts up to 2 months. If necessary, the treatment course may be repeated upon physician's recommendation, with an interval of 3–4 weeks.

Children. The drug is contraindicated in children under 7 years of age.

Overdose. Possible occurrence of dyspeptic symptoms and intensification of adverse reactions.

Adverse Reactions.

The medicinal product is generally well tolerated by patients. However, due to its multi-component composition, allergic reactions may occur, particularly in cases of individual hypersensitivity to any of the components or in case of improper administration regimen. These may include hyperemia, rash, itching, angioedema, contact dermatitis, and urticaria. Nettle leaves may cause pain in the lumbar region, changes in urine color, and discomfort at the end of urination. Although NEPHROFIT herbal blend contains only a small amount of nettle leaves, such symptoms cannot be completely ruled out.

If any adverse reactions occur, consult a physician immediately.

Shelf life. 2 years. Do not use after the expiry date stated on the packaging.

Storage conditions. Store in the original packaging at a temperature not exceeding 25 °C, in a place inaccessible to children.

Packaging. 1.5 g per filter bag, 20 bags per pack.

Availability. Over-the-counter (without prescription).

Manufacturer. EIM, Scientific and Production Pharmaceutical Company LLC.

Manufacturer's address and place of business. 20 lit. A-5, Kharkivs'kykh Dyviziy St., Kharkiv, Kharkiv region, 61091, Ukraine.