Triplixam

Patient Information Leaflet

Caution! Please keep this leaflet. Information on the immediate packaging is in a foreign language.
Triplixam (Tripliam), 10 mg + 2.5 mg + 5 mg, film-coated tablets
Perindoprilum argininum + Indapamidum + Amlodipinum
Triplixam and Tripliam are different brand names for the same medicine.
Please read this leaflet carefully before taking the medicine, as it contains
important information for the patient.

• Keep this leaflet so that you can read it again if necessary.
• If you have any questions, please consult your doctor or pharmacist.
• This medicine has been prescribed for a specific individual. Do not pass it on to others. This medicine may harm other people, even if their symptoms are the same.
• If you experience any adverse reactions, including any not listed in this leaflet, inform your doctor, pharmacist, or nurse. See section 4.

Table of Contents:

1. What Triplixam is and what it is used for
2. Important information before taking Triplixam
3. How to take Triplixam
4. Possible side effects
5. How to store Triplixam
6. Contents of the pack and other information

1. What Triplixam is and what it is used for

Triplixam is a combination medicine containing three active substances: perindopril,
indapamide, and amlodipine. It is an antihypertensive medicine used to treat high
arterial pressure (hypertension).
Patients already taking perindopril and indapamide in one medicine and amlodipine in another may instead take a single Triplixam tablet containing these three active substances at the same doses.
Each of the active substances helps lower blood pressure, and together they enable control of the patient's blood pressure:

• Perindopril belongs to a group of medicines called angiotensin-converting enzyme (ACE) inhibitors. It works by dilating blood vessels, making it easier for the heart to pump blood through them.
• Indapamide is a diuretic (belonging to a group of medicines called sulfonamide derivatives with an indole ring). Diuretics increase the amount of urine produced by the kidneys. However, indapamide differs from other diuretics in that it causes only a slight increase in urine production.
• Amlodipine is a calcium antagonist (belonging to a group of medicines called dihydropyridines). It causes relaxation of blood vessels, facilitating blood flow through them.

2. Important information before using Triplixam

When not to use Triplixam:

• if the patient is allergic to perindopril or other ACE inhibitors, indapamide or other sulfonamides, amlodipine or other dihydropyridines, or to any of the other ingredients of this medicine (listed in section 6);

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• if the patient has previously experienced symptoms during treatment with an ACE inhibitor such as wheezing, facial or tongue swelling, intense itching, or severe skin rash, or if such symptoms occurred in the patient or a family member under any other circumstances (a condition known as angioedema);
• if the patient has severe liver disease or a condition called hepatic encephalopathy (a brain dysfunction caused by liver disease);
• if untreated, uncontrolled heart failure is suspected in the patient (severe fluid retention, difficulty breathing);
• if the patient has aortic valve stenosis (narrowing of the aorta) or cardiogenic shock (a condition in which the heart cannot supply enough blood to the body);
• if the patient has heart failure following a heart attack;
• if the patient has very low blood pressure (hypotension);
• if the patient has low potassium levels in the blood;
• if the patient has severe kidney disease causing reduced blood supply to the kidneys (renal artery stenosis);
• if the patient is undergoing dialysis or blood filtration by another method. Depending on the device used, Triplixam may not be suitable for the patient;
• if the patient has moderate kidney disease;
• after the 3rd month of pregnancy (it is also advisable to avoid using Triplixam in early pregnancy – see the section on pregnancy);
• if the patient has diabetes or kidney dysfunction and is being treated with a blood pressure-lowering medicine containing aliskiren;
• if the patient has taken or is currently taking a combination medicine containing sacubitril and valsartan, used in the treatment of heart failure, as this increases the risk of angioedema (rapid swelling of tissues under the skin in the throat area) (see "Warnings and precautions" and "Triplixam with other medicines").

Warnings and precautions
If any of the following conditions apply to the patient, consult a doctor or pharmacist before using Triplixam:

• if the patient has hypertrophic cardiomyopathy (a heart muscle disease) or renal artery stenosis (narrowing of the blood vessel supplying blood to the kidney);
• if the patient has heart failure or any other heart disease;
• if the patient has significantly increased blood pressure (hypertensive crisis);
• if the patient has liver disease;
• if the patient has a collagen vascular disease, such as systemic lupus erythematosus or scleroderma;
• if the patient has atherosclerosis (hardening of the arteries);
• if the patient is undergoing parathyroid function tests;
• if the patient has gout;
• if the patient has diabetes;
• if the patient is on a low-salt diet or using potassium-containing salt substitutes (adequate potassium levels in the blood are important);
• if the patient is taking lithium or potassium-sparing diuretics (spironolactone, triamterene), as their use with Triplixam should be avoided (see "Triplixam with other medicines");
• if the patient is elderly and the dose needs to be increased;
• if the patient has previously had light-sensitive allergic reactions;
• in black patients, angioedema (swelling of the face, lips, mouth, tongue, or throat, which may cause difficulty swallowing or breathing) may occur more frequently, and the medicine may be less effective in lowering blood pressure;
• if the patient is undergoing dialysis with high-flux membranes;
• if the patient has kidney disease or is on dialysis;
• if the patient experiences worsening vision or eye pain. These may be symptoms of fluid accumulation in the choroid layer of the eye (choroidal effusion) or increased intraocular pressure, which may occur within hours or weeks of taking Triplixam. If left untreated, Page 2 of 10

these symptoms may lead to permanent vision loss. If the patient previously had an allergy to penicillin or sulfonamides, the risk of these disorders is higher.

• if the patient has muscle disorders, including pain, tenderness, weakness, or muscle cramps;
• if the patient has abnormally high levels of a hormone called aldosterone in the blood (primary hyperaldosteronism);
• if there is excessive acid in the blood, which may cause rapid breathing;
• if the patient has cerebral circulatory insufficiency (low blood pressure in the brain);
• if the patient develops swelling of the face, lips, mouth, tongue, or throat, which may cause difficulty swallowing or breathing (angioedema), which may occur at any time during treatment – treatment must be stopped immediately and medical advice sought;
• if the patient is taking any of the following medicines, as they increase the risk of angioedema:
• racecadotril (used to treat diarrhoea);
• sirolimus, everolimus, temsirolimus, and other medicines belonging to the group of so-called mTOR inhibitors (used to prevent organ transplant rejection and in cancer treatment);
• sacubitril (available in a combination medicine containing sacubitril and valsartan), used in the treatment of chronic heart failure;
• linagliptin, saxagliptin, sitagliptin, vildagliptin, and other medicines belonging to the group of drugs known as gliptins (used in diabetes treatment);
• if the patient is taking any of the following medicines used to treat high blood pressure:
• an angiotensin II receptor antagonist (AIIRA), also known as a sartan – e.g. valsartan, telmisartan, irbesartan, especially if the patient has kidney dysfunction related to diabetes,
• aliskiren. The doctor may recommend regular monitoring of kidney function, blood pressure, and blood electrolyte levels (e.g. potassium). See also the section "When not to use Triplixam".

The doctor may recommend blood tests to check for decreased sodium or potassium levels or increased calcium levels.
Inform your doctor if you are pregnant, planning pregnancy, or suspect pregnancy. Use of Triplixam is not recommended in early pregnancy and must not be used after the 3rd month of pregnancy, as it may seriously harm the unborn child (see section "Pregnancy and breastfeeding").
When using Triplixam, inform your doctor or healthcare provider if:

• the patient is to undergo anaesthesia and/or surgery;
• diarrhoea or vomiting has recently occurred, or the patient is dehydrated;
• LDL apheresis (mechanical removal of cholesterol from the blood) is planned;
• desensitisation treatment is planned to reduce allergic reactions after bee or wasp stings;
• a diagnostic test requiring iodine-containing contrast agents (substances allowing visualisation of organs such as the kidney or stomach in X-ray imaging) is to be performed.

Athletes should be aware that Triplixam contains an active substance (indapamide) that may lead to a positive result in anti-doping tests.
Children and adolescents
Do not give Triplixam to children or adolescents.
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Triplixam with other medicines
Inform your doctor or pharmacist about all medicines currently or recently taken, as well as any medicines the patient plans to take.
Patients with diabetes or kidney disease must not take aliskiren (used to treat high blood pressure).
Avoid taking Triplixam with:

• lithium (used to treat certain mental disorders such as mania, bipolar disorder, and recurrent depression);
• potassium-sparing medicines (triamterene, amiloride), potassium supplements, or potassium-containing salt substitutes, and other medicines that may increase potassium levels in the body (such as heparin, a medicine used to thin the blood to prevent clots; trimethoprim and co-trimoxazole, also known as a combination medicine containing trimethoprim and sulfamethoxazole, used to treat bacterial infections);
• dantrolene (intravenous), also used to treat malignant hyperthermia occurring during anaesthesia (symptoms include very high fever and muscle rigidity);
• estramustine (used in cancer treatment);
• medicines used to treat diarrhoea (racecadotril) or medicines used to prevent organ transplant rejection (sirolimus, everolimus, temsirolimus, and other medicines belonging to the group of so-called mTOR inhibitors). See section "Warnings and precautions".
• a combination medicine containing sacubitril and valsartan (used in the treatment of chronic heart failure). See sections "When not to use Triplixam" and "Warnings and precautions".
• other medicines used to treat high blood pressure: angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor antagonists.

Other medicines may affect treatment with Triplixam. The doctor may recommend dose adjustments and/or additional precautions. Inform your doctor if the patient is taking any of the following medicines, as special precautions may be required:

• other medicines used to treat high blood pressure, including angiotensin II receptor antagonists (AIIRAs), aliskiren (see also sections "When not to use Triplixam" and "Warnings and precautions"), or diuretics (medicines that increase urine production by the kidneys);
• potassium-sparing medicines used in heart failure treatment: eplerenone and spironolactone at doses from 12.5 mg to 50 mg per day;
• anaesthetics;
• iodine-containing contrast agents;
• bepridil (used to treat angina pectoris);
• methadone (used in addiction treatment);
• medicines used to treat heart rhythm disorders (e.g. dofetilide, ibutilide, bretylium, cizapride, difemanil, procainamide, quinidine, hydroquinidine, disopyramide, amiodarone, sotalol);
• verapamil, diltiazem (used in heart diseases);
• digoxin or other cardiac glycosides (used in heart diseases);
• antibiotics used to treat bacterial infections (e.g. rifampicin, intravenous erythromycin, clarithromycin, sparfloxacin, moxifloxacin);
• antifungal medicines (e.g. itraconazole, ketoconazole, intravenous amphotericin B);
• allopurinol (used to treat gout);
• antihistamines used to treat allergic reactions such as hay fever (e.g. mizolastine, terfenadine, astemizole);
• corticosteroids used to treat various diseases, including severe asthma and rheumatoid arthritis, and non-steroidal anti-inflammatory drugs (e.g. ibuprofen) or high doses of salicylates (e.g. acetylsalicylic acid, a substance found in many medicines used for pain, fever, and prevention of blood clots); Page 4 of 10
• immunosuppressive medicines (given to control immune system reactions) used in autoimmune diseases or after organ transplantation (e.g. cyclosporine, tacrolimus);
• tetracosactide (used to treat Crohn's disease);
• gold salts, especially when administered intravenously (used to treat symptoms of rheumatoid arthritis);
• halofantrine (used to treat certain types of malaria);
• baclofen used to treat muscle stiffness in diseases such as multiple sclerosis;
• medicines used to treat diabetes, such as insulin or metformin;
• calcium, including calcium supplements;
• stimulant laxatives (e.g. senna);
• medicines used to treat cancer;
• vinpocetine (used to treat symptomatic cognitive disorders in elderly patients, including memory loss);
• medicines used to treat mental disorders such as depression, anxiety, schizophrenia (e.g. tricyclic antidepressants, antipsychotics, imipramine-type antidepressants, neuroleptics such as amisulpride, sulpiride, sultopride, tiapride, haloperidol, droperidol);
• pentamidine (used to treat pneumonia);
• ritonavir, indinavir, nelfinavir (so-called protease inhibitors used in HIV treatment);
• Hypericum perforatum (St. John's wort);
• trimethoprim (used to treat infections);
• medicines used to treat low blood pressure, shock, or asthma (e.g. ephedrine, noradrenaline, or adrenaline);
• nitroglycerin and other nitrates or other vasodilating medicines, as they may additionally lower blood pressure.

Triplixam with food and drink
Do not consume grapefruit or grapefruit juice while taking Triplixam, as this may increase the concentration of the active substance – amlodipine – which could lead to an unexpected intensification of Triplixam's blood pressure-lowering effect.
Pregnancy and breastfeeding
If the patient is pregnant or breastfeeding, suspects she may be pregnant, or is planning to have a child, she should consult a doctor or pharmacist before using this medicine.
Pregnancy
Inform your doctor if you are pregnant, suspect pregnancy, or are planning pregnancy. Usually, the doctor will recommend discontinuing Triplixam before planned pregnancy or immediately after pregnancy is confirmed and will recommend using an alternative medicine instead of Triplixam. Use of Triplixam is not recommended in early pregnancy and must not be used after the 3rd month of pregnancy, as it may seriously harm the unborn child.
Breastfeeding
Inform your doctor if you are breastfeeding or plan to breastfeed. Use of Triplixam is not recommended during breastfeeding, especially when nursing a newborn or premature infant. The doctor may recommend using another medicine.
Driving and operating machinery
Triplixam may affect the ability to drive or operate machinery. If taking the medicine causes nausea, dizziness, fatigue, or headache, do not drive or operate machinery and contact your doctor immediately.
Triplixam contains sodium
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Triplixam contains less than 1 mmol of sodium (23 mg) per tablet, meaning the medicine is considered "sodium-free".

3. How to use Triplixam

This medicine should always be taken exactly as directed by the doctor or pharmacist. If in doubt,
consult the doctor or pharmacist.
Triplixam is available in the following strengths:
5 mg + 1,25 mg + 5 mg;
5 mg + 1,25 mg + 10 mg;
10 mg + 2,5 mg + 5 mg;
10 mg + 2,5 mg + 10 mg.
The tablet should be swallowed with a glass of water, preferably in the morning, before a meal. The doctor will determine
the appropriate dose for the patient. Usually, the recommended dose is one tablet once daily.

Taking more Triplixam than prescribed
Taking too many tablets may cause blood pressure to drop, even to dangerous levels, which may sometimes be accompanied by nausea, vomiting, cramps, dizziness, drowsiness, disorientation, oliguria (passing less urine than usual), anuria (lack of urine production or excretion).
The patient may feel a "void" in the head, experience faintness or weakness. If the drop in blood pressure is severe, shock may occur, characterized by cold and clammy skin, and the patient may lose consciousness.
Breathing difficulties due to fluid accumulation in the lungs (pulmonary edema) may occur even 24–48 hours after taking the medicine.
If too many Triplixam tablets have been taken, seek immediate medical advice from a doctor or go to the nearest hospital emergency department without delay.

Missing a dose of Triplixam
It is important to take the medicine every day, as regular use ensures more effective treatment. However, if a dose of Triplixam is missed, the next dose should be taken at the usual time. A double dose must not be taken to make up for the missed dose.

Stopping Triplixam treatment
Treatment for high blood pressure is usually long-term; therefore, consult the doctor before stopping this medicine.
If there are any further doubts about the use of this medicine, consult the doctor or pharmacist.

4. Possible adverse effects

Like all medicines, this medicine can cause adverse effects, although not everyone will experience them.
If the patient experiences any of the following serious adverse symptoms, the medicine must be discontinued immediately and medical advice must be sought without delay:

• sudden onset of wheezing, chest pain, shortness of breath or difficulty breathing (uncommon – may occur in less than 1 in 100 patients);

• swelling of the eyelids, face or lips (uncommon – may occur in less than 1 in 100 patients);

• swelling of the mucous membranes of the mouth, tongue or throat, causing significant breathing difficulties (uncommon – may occur in less than 1 in 100 patients);

• severe skin reactions, including severe rash, urticaria, redness of the entire skin surface, intense itching, blistering, peeling and swelling of the skin, mucosal inflammation (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions (very rare – may occur in less than 1 in 10,000 patients);

• severe dizziness or fainting (common – may occur in less than 1 in 10 patients);

• heart attack (very rare – may occur in less than 1 in 10,000 patients), life-threatening heart rhythm disturbances (frequency unknown);

• pancreatitis, which may cause severe upper abdominal pain radiating to the back and general malaise (very rare – may occur in less than 1 in 10,000 patients);

• muscle weakness, cramps, tenderness or pain, particularly if the patient also feels unwell or has a high temperature, which may be due to abnormal muscle breakdown (frequency unknown).

Adverse effects, grouped by decreasing frequency:

• very common (affects at least 1 in 10 patients): oedema (fluid retention).

• common (affects less than 1 in 10 patients): low blood potassium levels, headache, central dizziness, palpitations (awareness of heartbeat), sudden flushing of the face and neck, vestibular dizziness, tingling/numbness, visual disturbance, double vision, tinnitus (sensation of hearing sounds), feeling of "emptiness" in the head due to low blood pressure, cough, shortness of breath, gastrointestinal disorders (nausea, vomiting, abdominal pain, taste disturbances, indigestion or digestive disturbances, diarrhoea, constipation, change in bowel habits), allergic reactions (such as rash, itching), muscle cramps, feeling of fatigue, weakness, drowsiness, swelling of the ankle area.

• uncommon (affects less than 1 in 100 patients): mood swings, anxiety, depression, sleep disturbances, tremor, urticaria, fainting, insensitivity to pain, irregular and/or rapid heartbeat, rhinitis (nasal mucosa inflammation – swelling or nasal discharge), hair loss, purpura (small red spots on the skin), skin discolouration, itching, sweating, chest pain, muscle or joint pain, back pain, pain, malaise, kidney disorders, urinary disorders, need to urinate at night, increased frequency of urination, impotence (inability to achieve or maintain an erection), fever or elevated body temperature, discomfort or enlargement of the breasts in men, weight gain or weight loss, increased number of a certain type of white blood cells, high blood potassium levels, hypoglycaemia (very low blood sugar levels), low blood sodium levels, which may lead to dehydration and low blood pressure, vasculitis (inflammation of blood vessels), photosensitivity reaction (skin changes) after exposure to sunlight or artificial UVA rays, clusters of blisters on the skin, swelling of hands or feet, increased blood creatinine and urea levels, falls, dryness of the oral mucosa.

• rare (affects less than 1 in 1,000 patients): disorientation, abnormal laboratory test results: low blood chloride levels, low blood magnesium levels, increased liver enzyme activity, elevated serum bilirubin levels; worsening of psoriasis, reduced or absent urine output, acute kidney failure. Dark-coloured urine, nausea or vomiting, muscle cramps, disorientation and seizures. These may be symptoms of a condition called SIADH (syndrome of inappropriate antidiuretic hormone secretion).

• very rare (affects less than 1 in 10,000 patients): decreased number of white blood cells, decreased number of platelets (leading to easy bruising and nosebleeds), anaemia (reduced number of red blood cells), angina pectoris (chest pain, jaw and back pain triggered by physical exertion and caused by impaired blood supply to the heart), eosinophilic pneumonia (a rare type of lung inflammation), gum swelling, severe skin reactions including severe rash, redness of the entire skin surface, intense itching, blistering, peeling and swelling of the skin, erythema multiforme (rash, often starting with red, itchy spots on the face, arms or legs), bleeding, tender or enlarged gums, liver function disorders, hepatitis, severe kidney function impairment, yellowing of the skin (jaundice), abdominal distension (gastritis), nerve disorders causing weakness, tingling or numbness, increased muscle tone, hyperglycaemia (very high blood sugar levels), high blood calcium levels, stroke, possibly secondary to marked drop in blood pressure.

• frequency not known (cannot be estimated from available data): hepatic encephalopathy (brain disorder caused by liver disease), abnormal ECG (electrocardiogram) findings; in patients with systemic lupus erythematosus (a type of collagenosis), symptoms may worsen. Short-sightedness, blurred vision, worsening of vision or eye pain due to high pressure (possible symptoms of fluid accumulation in the choroid layer of the eye (choroidal effusion) or acute angle-closure glaucoma). Tremor, rigidity, facial masking, slowed movements and dragging gait, unsteady gait. Discolouration, numbness and pain in fingers or toes (Raynaud's phenomenon).

Changes in laboratory test results (blood tests) may occur. Your doctor may recommend blood tests to monitor your health.
If any of these symptoms occur, contact your doctor as soon as possible.
Reporting of adverse effects
If you experience any adverse effects, including any not listed in this leaflet, inform your doctor, pharmacist or nurse. Adverse effects can be reported directly to the Department for Monitoring Adverse Drug Reactions, Office for Registration of Medicinal Products, Medical Devices and Biocidal Products
Al. Jerozolimskie 181C
02-222 Warsaw
Phone: +48 22 49 21 301
Fax: +48 22 49 21 309
Website: https://smz.ezdrowie.gov.pl
Reporting adverse effects helps to provide more information on the safety of this medicine.

5. How to store Triplixam

Keep this medicine out of sight and reach of children.
Do not use this medicine after the expiry date stated on the packaging. The expiry date refers to the last day of the stated month.
No special storage instructions apply.
Shelf-life after first opening the container: 30 days.
Medicines must not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Triplixam contains

• The active substances in this medicine are: perindopril with arginine, indapamide and amlodipine. Page 8 of 10

One coated tablet of Triplixam contains 6.790 mg of perindopril (as 10 mg
perindopril arginine), 2.5 mg of indapamide and 6.935 mg of amlodipine besylate (equivalent to
5 mg of amlodipine).

• Other components of the tablet are:
• tablet core: calcium carbonate with starch composed of: calcium carbonate (90%), pregelatinized starch, maize (10%); microcrystalline cellulose, sodium croscarmellose, magnesium stearate, colloidal anhydrous silica, pregelatinized starch.
• tablet coating: glycerol, hypromellose 6 mPa·s, polyethylene glycol 6000, magnesium stearate, titanium dioxide (E 171).

What Triplixam looks like and contents of the pack
Triplixam 10 mg + 2.5 mg + 5 mg is a white, elongated film-coated tablet, 11.5 mm long and

6.09 mm wide, with an embossed mark on one side and an embossed mark on the other side.
Tablets are available in cardboard boxes containing 30, 60 (2 containers of 30 tablets each) or 90
(3 containers of 30 tablets each) tablets.
A desiccant is placed in the lid closing the tablet container.

For further information, please contact the Marketing Authorisation Holder or Parallel Importer:
Marketing Authorisation Holder in Italy, country of export:
Les Laboratoires Servier, 50, rue Carnot, 92284 Suresnes cedex, France
Manufacturer:
Servier (Ireland) Industries Ltd, Gorey Road, Arklow - Co. Wicklow, Ireland
Les Laboratoires Servier Industrie, 905 route de Saran, 45520 Gidy, France
Anpharm Przedsiębiorstwo Farmaceutyczne S.A., ul. Annopol 6b, 03-236 Warsaw, Poland
EGIS Pharmaceuticals PLC, Mátyás király u.65, H-9900 Körmend, Hungary
Parallel Importer:
Delfarma Sp. z o.o., ul. Św. Teresy od Dzieciątka Jezus 111, 91-222 Łódź, Poland
Repackaged by:
Delfarma Sp. z o.o., ul. Św. Teresy od Dzieciątka Jezus 111, 91-222 Łódź, Poland
Marketing Authorisation number in Italy, country of export: 042407167
Parallel Import Licence Number: 214/25
This medicinal product is authorised for sale in the European Economic Area (EEA) under the following names:
Belgium TRIPLIXAM, comprimé pelliculé
Bulgaria TRIPLIXAM, филмирани таблетки
Croatia TRIPLIXAM, filmom obložene tablete
Cyprus TRIPLIXAM, επικαλυμμένα με λεπτό υμένιο δισκία
Czech Republic TRIPLIXAM
Estonia TRIPLIXAM
Finland TRIPLIXAM, kalvopäällysteinen tabletti
France TRIPLIXAM, comprimé pelliculé
Greece TRIPLIXAM, επικαλυμμένα με λεπτό υμένιο δισκία
Ireland COVERDINE film-coated tablets
Italy TRIPLIAM, compresse rivestite con film
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Latvia TRIPLIXAM, apvalkotas tabletes
Lithuania TRIPLIXAM, plėvele dengtos tabletės
Luxembourg TRIPLIXAM, comprimé pelliculé
Malta TRIPLIXAM film-coated tablets
Netherlands TRIPLIXAM, filmomhulde tabletten
Poland TRIPLIXAM
Portugal TRIPLIXAM
Romania TRIPLIXAM comprimate filmate
Slovakia TRIPLIXAM, filmom obalené tablety
Slovenia TRIPLIXAM filmsko obložene tablete
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