Taufon

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT TAUFON

Composition:

Active substance: taurine;

1 ml of eye drops contains 40 mg of taurine;

Excipients: methylparahydroxybenzoate (E 218), water for injections.

Pharmaceutical form. Eye drops.

Main physicochemical properties: clear, colorless liquid.

Pharmacotherapeutic group. Agents used in ophthalmology. Trophic agents.

ATC code S01XA.

Pharmacological Properties.

Pharmacodynamics.

Taurine belongs to amino acids that stimulate reparative and regenerative processes in dystrophic diseases of the retina, traumatic injuries of ocular tissues, and pathological conditions accompanied by severe disturbances in the metabolism of these tissues. As a sulfur-containing amino acid, the drug promotes normalization of cell membrane functions, optimization of energy and metabolic processes, maintenance of stable electrolyte composition of cellular cytoplasm, and inhibition of synaptic transmission (neuromodulator role).

Pharmacokinetics.

When administered as eye drops, the drug penetrates into the interior of the eye, where it exerts its specific effect. When used at therapeutic doses, taurine is practically not absorbed into the systemic bloodstream.

Clinical characteristics.

Indications.

Dystrophic lesions of the cornea and retina, including hereditary tapetoretinal degenerations; senile, diabetic, traumatic, and radiation cataracts; as a stimulant of reparative processes in corneal injuries; as an additional agent in the treatment of open-angle glaucoma.

Contraindications.

Individual hypersensitivity to the components of the drug.

Interaction with other medicinal products and other forms of interaction.

When used concomitantly with timolol eye drops, a potentiated reduction in intraocular pressure as well as a potentiated reduction in arterial pressure may occur.

Special precautions for use.

In open-angle glaucoma, the drug should be used in combination with timolol, administered 20–30 minutes before instilling timolol.

The medicinal product contains methylparaben (E 218), which may cause allergic reactions (possibly delayed).

Use during pregnancy or breastfeeding.

There is no data available on the use of the drug during pregnancy or breastfeeding.

Ability to affect reaction speed when driving or operating machinery.

The effect of the drug on the human body during driving or operating machinery has not been studied.

Method of Administration and Dosage

The medication is intended for adults.

Opening the vial is performed by puncturing the top part of the neck with a twisting motion of the cap until it stops.

Immediately before use, it is recommended to hold the vial in the palm of the hand to warm it to body temperature. Instill 2–3 drops, 2–4 times daily, into the conjunctival sac of the affected eye.

The treatment course for injuries is 1 month; for cataracts — 3 months (repeat with a 1-month interval).

For the treatment of tapetoretinal degeneration and other retinal dystrophic diseases, as well as penetrating corneal injuries, the medication is administered subconjunctivally: 0.3 mL of the 4% solution once daily for 10 days. The course is repeated every 6–8 months.

For open-angle glaucoma, instill 2–3 drops into each conjunctival sac twice daily, 20–30 minutes before applying timolol. The treatment duration is determined individually.

Children. The efficacy and safety of the medication in children have not been studied; therefore, the medication should not be prescribed to this age group of patients.

Overdose.

There is no data on overdose of the medication.

Adverse reactions.

Allergic reactions such as allergic conjunctivitis due to individual hypersensitivity to the components of the drug may occur during administration of the medication. Ocular disorders: eye itching, conjunctival hyperemia, eye irritation (ocular burning and stinging).

Shelf life.

2 years. Do not use the drug after the expiry date stated on the packaging.

Shelf life of the drug after opening the bottle – 28 days.

Storage conditions.

Store in a protected from light place at a temperature not exceeding 25 °C.

Keep out of reach of children.

Packaging. 5 ml or 10 ml in a bottle. 1 bottle per carton.

Prescription status. Prescription only.

Manufacturer: JSC "Farmak".

Manufacturer's name and address of place of business.

74, Kyrylivska Street, Kyiv, 04080, Ukraine.