Pertussin

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT PERTUSSIN

Composition:

Active substances: liquid extract of thyme herb (Serpilli herba) (1 : 1), potassium bromide;

1 g of syrup contains: liquid extract of thyme herb (Serpilli herba) (1 : 1) (extractant – 30% ethanol) 120 mg, potassium bromide 10 mg;

Excipients: sugar syrup, 96% ethanol, purified water.

Pharmaceutical form. Syrup.

Main physicochemical characteristics: brown liquid with an aromatic odor.

Pharmacotherapeutic group. Medicinal products used for cough and colds. Expectorants. ATC code R05C A10.

Pharmacological properties.

Pharmacodynamics. Pertussin accelerates expectoration of sputum, has a soothing effect and produces a sedative action. The medicinal product stimulates mucociliary clearance. The presence in the extract of thyme of essential oil, tannins, and bitter substances causes irritation of nerve endings (mainly parasympathetic), which enhances secretion of liquid from bronchioles, reduces viscosity of bronchial secretions. It enhances expectoration of sputum, increases ciliated epithelium activity, improves drainage function of the bronchial tree.

Pharmacokinetics. Not studied.

Clinical characteristics.

Indications. Symptomatic treatment of inflammatory diseases of the respiratory tract accompanied by cough: bronchitis, tracheitis, pneumonia, whooping cough.

Contraindications.

Hypersensitivity to the components of the drug, including bromides or other plants of the Lamiaceae family, as well as sensitivity to celery and birch pollen (possible cross-reaction); children under 4 years of age; decompensated cardiovascular system, arterial hypotension, severe atherosclerosis, anemia, kidney diseases with impaired renal function, diabetes mellitus, alcoholism.

Interaction with other medicinal products and other forms of interaction. Unknown. When taking any other medicinal products simultaneously, inform your doctor!

Special precautions for use.

When using the drug, the recommended doses should be strictly followed.

For children aged 4 to 6 years, the preparation should be diluted with boiled water.

If during treatment with the drug symptoms worsen and/or dyspnea, fever, or purulent sputum occur, medical advice must be sought. If symptoms persist for one week, consult a physician.

This medicinal product contains 10–14 vol.% ethanol (alcohol), i.e. 1.7 g/dose (15 mL), equivalent to 34 mL of beer or 14 mL of wine per dose. It is harmful for patients suffering from alcoholism. Caution is advised when administering to pregnant and breastfeeding women, children, patients with liver disease, and patients with epilepsy.

Pertussin contains up to 11.4 g of sucrose per dose (15 mL). If you have been diagnosed with intolerance to certain sugars, consult your doctor before taking this medicinal product.

Use during pregnancy or breastfeeding.
Due to insufficient data, the use of this medicinal product is not recommended during these periods.

Ability to affect reaction speed when driving or operating machinery.
Since the preparation contains alcohol, patients should exercise caution when driving or operating machinery.

Dosage and Administration.

For oral use. Adults and children aged 12 years and older: 1 tablespoon (15 ml) three times a day.

Children aged 4 to 6 years: ½ teaspoon (2.5 ml) three times a day; aged 6 to 9 years: 1 teaspoon (5 ml) three times a day; aged 9 to 12 years: 1 dessert spoon (10 ml) three times a day.

For children under 6 years of age, a single dose of the medication—½ teaspoon (2.5 ml)—should be dissolved in 2 dessert spoons (20 ml) of cooled boiled water.

The duration of treatment is determined by the physician, depending on the course of the disease, the nature of combination therapy, and the patient's tolerance to the medication.

Children. To be used in children aged 4 years and older under medical prescription.

Overdose.

In case of overdose, adverse effects may be intensified. Treatment is symptomatic.

Adverse reactions.

With prolonged use, symptoms of bromism are possible: skin rashes, rhinitis, conjunctivitis, gastroenterocolitis, general weakness, ataxia, bradycardia. Treatment of bromism consists of discontinuing the drug and enhancing elimination of bromide salts (administration of large amounts of sodium chloride, fluids, and diuretics).

Gastrointestinal disturbances (including nausea, vomiting, diarrhea) are possible.

Allergic reactions to the components of the drug are possible.

In case of any adverse events, consult a physician immediately!

Shelf life. 4 years.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C.

Keep out of reach of children.

Do not use the drug after the expiry date stated on the package!

Packaging. 50 g or 100 g in bottles. 100 g or 200 g in bottles with tamper-evident closure. 200 g in bottles with tamper-evident closure; 1 bottle per carton.

Prescription status. Over-the-counter.

Manufacturer.

JSC "FITOFARM".

Manufacturer's address and place of business.

Sibirceva St., 2, Bakhmut, Donetsk region, 84500, Ukraine.

Marketing authorization holder.

JSC "FITOFARM".

Address of the marketing authorization holder.

Almatinska St., 12, Kyiv, 02092, Ukraine.