Glodu tincture
Ukraine
INSTRUCTION |
CRATAEGUS TINCTURE |
Composition:Active ingredient: hawthorn fruit tincture; One bottle of the medicinal product contains hawthorn fruit tincture (Crataegi fructus) (1 : 10) (extraction solvent — 70% ethanol) 100 ml. |
| Pharmaceutical form. Tincture. Main physicochemical properties: clear yellowish-red liquid. Sediment may form during storage. |
| Pharmacotherapeutic group. Agents used in cardiology. ATC Code C01EB04. |
Pharmacological properties.Pharmacodynamics. Biologically active substances present in hawthorn fruits (flavonoids, choline, acetylcholine, tannins, phytosterols, triterpenic acids) enhance blood circulation in coronary vessels of the heart and cerebral vessels, increase myocardial sensitivity to cardiac glycosides, moderately strengthen cardiac muscle contraction, and reduce its excitability. Pharmacokinetics. The medicinal product is well absorbed when administered orally. The effect occurs within |
Clinical characteristics.Indications. Functional disorders of the cardiovascular system (including neurocirculatory dystonia). Also used as an adjunctive medicinal product in mild forms of cardiac arrhythmias (atrial fibrillation, paroxysmal tachycardia). |
| Contraindications. Marked arterial hypotension, bradycardia, hypersensitivity to biologically active substances contained in the medicinal product. |
Interaction with other medicinal products and other forms of interactions. Hawthorn tincture potentiates the action of antiarrhythmic agents. The medicinal product enhances the effects of cardiac glycosides, hypnotics, sedatives, and antihypertensive agents. Concomitant use with alkaloid salts is not recommended due to the possibility of forming negative complexes. The medicinal product should not be used together with cisapride. If simultaneous use of any medicinal products is necessary, consult a physician. |
Special precautions.The product is not recommended to be taken during meals to avoid interaction with food components. Hawthorn tincture is a conventional herbal medicinal product intended for use according to indications supported by long-term use. This medicinal product contains 69% v/v ethanol (alcohol), i.e., 272 mg/dose. Harmful for patients suffering from alcoholism. Caution should be exercised when administering to patients with liver disease and those with epilepsy. Use during pregnancy or breastfeeding. The medicinal product is contraindicated in women during pregnancy and breastfeeding. Ability to influence reaction rate while driving or operating machinery. The medicinal product contains ethyl alcohol and may cause drowsiness; therefore, during treatment with this medicinal product, patients should refrain from driving vehicles or operating potentially hazardous machinery. |
Method and dosage.Administered orally before meals. Adults are recommended to take 20 drops of tincture If the bottle does not have a dropper cap, a glass medical pipette should be used; the dosage remains unchanged. Continue until a stable therapeutic effect is achieved. Treatment duration is determined individually by a physician. The patient should consult a physician if symptoms persist during treatment or if adverse reactions not listed in the instructions occur. Children. Do not use in children under 12 years of age due to the presence of ethanol in the medicinal product. |
| Overdose. Significant overdose may lead to drowsiness, bradycardia, and decreased arterial pressure, requiring discontinuation of the medicinal product and symptomatic therapy. |
Adverse reactions.Drowsiness, significant slowing of heart rate. Allergic reactions may occur (including hyperemia, rash, itching, skin swelling). In case of any adverse events, medical advice must be sought. Reporting of adverse reactions after medicinal product registration is highly important. It enables monitoring of the benefit-risk ratio during use of this medicinal product. Healthcare and pharmaceutical professionals, as well as patients or their legal representatives, should report all suspected adverse reactions and lack of efficacy through the Automated Information System for Pharmacovigilance at: https://aisf.dec.gov.ua. |
| Shelf life. 5 years. The medicinal product must not be used after the expiry date stated on the packaging. |
Storage conditions. Store in the original packaging at a temperature not exceeding 25 °C. Keep out of reach of children. |
| Packaging. 100 ml in glass bottles; 100 ml in polymer bottles. |
| Prescription status. Over-the-counter. |
| Manufacturer. LLC "MEDLEV". |
| Manufacturer's location and address of business activity. Ukraine, 49000, Dnipro, Shevchenka St., 37. |