A-diston

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT A-DISTON (A-DISTON)

Composition:

Active ingredient: tincture of medicinal plant raw materials: hawthorn fruits (Crataegi fructus), motherwort herb (Leonuri cardiaca herba), valerian roots (Valerianae radix), fennel fruits (Fructus fenniculi vulgaris), peppermint leaves (Menthae piperitae folium), arnica flowers (Arnicae flos) (extraction agent – 70% ethanol);

1 bottle of drops contains tincture of medicinal plant raw materials (1:10): hawthorn fruits (Crataegi fructus), motherwort herb (Leonuri cardiaca herba), valerian roots (Valerianae radix), fennel fruits (Fructus fenniculi vulgaris), peppermint leaves (Menthae piperitae folium), arnica flowers (Arnicae flos) (extraction agent – 70% ethanol) – 30 ml or 50 ml.

Pharmaceutical form. Oral drops.

Main physicochemical characteristics: clear, light brown liquid with a pleasant odour.

Pharmacotherapeutic group.
Combined cardiological preparations. ATC code C01EX.

Pharmacological properties.

Pharmacodynamics.

A combined herbal preparation containing a complex of biologically active substances: from hawthorn fruits, which have hypotensive, cardioprotective, and spasmolytic properties; from dog nettle herb, which has hypotensive, sedative, and spasmolytic effects; from fennel fruits, which have spasmolytic action; from arnica flowers, which have tonic and cardioprotective activity; and from mint leaves, which have spasmolytic and sedative effects. The drug enhances blood circulation in cerebral and coronary vessels, reduces myocardial excitability, and has hepatoprotective, antiarrhythmic, and calming properties.

Clinical characteristics.

Indications.

Used in the complex treatment of functional disorders of the cardiovascular system accompanied by arrhythmia, ischemia, and hypoxia (neurocirculatory dystonia, vegetative neurosis) for the purpose of cardioprotection. Used as an auxiliary medicinal agent in mild forms of cardiac rhythm disturbances.

Contraindications.

Hypersensitivity to the components of the drug, allergy to plants of the Asteraceae family; history of alcoholism, concomitant use of medications containing alcohol; peptic ulcer of the stomach and duodenum; liver cirrhosis; pronounced arterial hypotension or bradycardia; depression and other disorders accompanied by suppression of central nervous system activity; bronchial asthma.

Interaction with other medicinal products and other types of interactions.

Since the drug A-Diston contains 70 % ethyl alcohol, the effect of sedatives, tranquilizers, and neuroleptics may be potentiated; preparations of dog nettle, valerian, and hawthorn may potentiate the pharmacological effects of sedatives, hypnotics, analgesics, antihypertensives, and cardiac glycosides, as well as enhance the effect of alcohol.

Special precautions for use.

During treatment with the drug, consumption of alcoholic beverages should be avoided. Blood pressure must be monitored during the treatment period. Prolonged use and high doses of the drug may impair digestion, cause headaches, stimulate the nervous system, and in patients with cardiovascular diseases, may worsen cardiac function. Patients with gastroesophageal reflux should avoid preparations containing peppermint leaf, as heartburn may increase. The drug should be used with caution in patients with cholelithiasis and other biliary tract disorders.

Use during pregnancy or breastfeeding.

Contraindicated.

Ability to affect reaction speed when driving or operating machinery.

Driving vehicles or operating potentially hazardous machinery is prohibited during treatment with this drug.

Method of administration and dosage.

For adults, take 20–30 drops orally three times daily before meals. The duration of treatment is determined individually by a physician and averages 30 days.

Children. There is no experience with the use of the drug in children.

Overdose.

With a significant increase in dose, dyspeptic disorders and signs of hypersensitivity may occur. Rarely – drowsiness, decreased arterial pressure, bradycardia, feelings of depression, increased fatigue, dizziness, headache, nausea, and in patients with cardiovascular diseases – chest pain, requiring discontinuation of the drug and administration of symptomatic therapy.

Adverse Reactions.

Possible allergic reactions (including hyperemia, rash, itching, and skin swelling); gastrointestinal disturbances, including dyspeptic disorders, dry mouth, nausea, vomiting, constipation or diarrhea, abdominal pain; rarely – sleep disturbances, drowsiness; decreased heart rate; dizziness; headache, fatigue, weakness, depression, reduced mental and physical performance; polyuria; sweating, chills.

Shelf life.

2 years.

Do not use the medicinal product after the expiry date stated on the packaging.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 °C. Keep out of reach of children. Sedimentation may occur during storage.

Packaging.

30 ml or 50 ml in a bottle. One bottle per cardboard box.

Supply classification.

Over-the-counter.

Manufacturer.

JSC "Biolyk".

Manufacturer's name and address of the place of business.

131 Sh. Nezalezhnosti Str., Ladizhin, Vinnytsia Oblast, 24321, Ukraine.

Marketing Authorization Holder.

LLC "Ukrainian Pharmaceutical Company".

Address of the Marketing Authorization Holder.

1 U. Starosilska Str., Kyiv, 02660, Ukraine.