Lincaz sugar-free

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT Linkus sugar free (Linkus sugar free)

Composition:

Active substances: 10 ml of syrup contains: Adhatoda vasica leaf extract, thick (5:1), (extraction solvent purified water) – 120 mg; Glycyrrhiza glabra root extract, thick (4.17:1), (extraction solvent purified water) – 18 mg; Piper longum fruit extract, thick (4:1), (extraction solvent purified water) – 25 mg; Viola odorata flower extract, thick (4.17:1), (extraction solvent purified water) – 6 mg; Hyssopus officinalis leaf extract, thick (4.17:1), (extraction solvent water) – 12 mg; Alpinia galanga root extract, thick (4.17:1), (extraction solvent purified water) – 12 mg; Cordia latifolia fruit extract, thick (4:1), (extraction solvent purified water) – 25 mg; Althaea officinalis seed extract, thick (4:1), (extraction solvent purified water) – 25 mg; Zizyphus vulgaris fruit extract, thick (4:1), (extraction solvent purified water) – 25 mg; Onosma bracteatum leaf extract, thick (4:1), (extraction solvent purified water) – 25 mg;

Excipients: propylene glycol, sodium saccharin, sorbitol solution (E 420), glycerin, anhydrous citric acid, methylparaben (E 218), propylparaben (E 216), peppermint oil, clove oil, purified water.

Pharmaceutical form. Syrup.

Main physicochemical properties: brown syrup with a characteristic odor.

Pharmacotherapeutic group.

Preparations used for cough and colds. Expectorants. Combinations. ATC code R05C A10.

Pharmacological properties.

Pharmacodynamics.

A complex herbal medicinal product with anti-inflammatory, expectorant, mucolytic, spasmolytic, and antipyretic properties. It activates the secretory function of the respiratory epithelium, alters the surface activity of pulmonary surfactant, stimulates ciliary epithelial function, thereby exerting a positive effect on exudative and proliferative phases of inflammation. It liquefies thick sputum and facilitates the clearance of mucus from the respiratory tract. Acts on the mucous membranes of the pharynx and bronchi as a local antiseptic.

Administration of the medicinal product reduces the tone of smooth muscles of bronchioles and trachea, increases the diameter of bronchioles and alveolar sacs, and decreases edema of mucous membranes. Changes in cough intensity are observed within 3–4 days of taking the medicinal product.

Pharmacokinetics.

Pharmacokinetic data are unavailable.

Clinical characteristics.

Indications.

Complex therapy of inflammatory diseases of the upper and lower respiratory tract accompanied by dry, irritating cough; bronchitis (acute and chronic); pharyngitis, tracheitis, tracheobronchitis.

Contraindications.

Hypersensitivity to any component of the medicinal product. Organic heart lesions (myocarditis, pericarditis, myocardial infarction), arterial hypertension; hepatic and renal dysfunction; hypokalemia; severe obesity.

Hereditary fructose intolerance or galactose malabsorption.

Contraindicated in children under 1 year of age.

Interaction with other medicinal products and other forms of interaction.

Concomitant use of this medicinal product with antitussive agents that suppress expectoration (e.g., codeine) is not recommended.

If simultaneous use of any other medicinal products is necessary, inform your doctor.

Special precautions.

The syrup is sugar-free and therefore can be used by patients with diabetes mellitus and by those on a low-calorie diet.

If a respiratory illness is accompanied by difficulty breathing, fever, purulent or bloody sputum, a physician should be consulted.

The medicinal product contains sorbitol solution, which may exert a mild laxative effect. The energy value of 1 g of sorbitol is 2.6 kcal.

Administration of 400 mg/kg of propylene glycol in adults and 200 mg/kg in children may cause symptoms similar to those occurring after alcohol consumption.

Experimental and clinical studies indicate that the use of the medicinal product "Linkas Sugar Free" is safe in elderly patients.

Important information about excipients.

The medicinal product contains auxiliary substances such as methylparaben and propylparaben, which may cause allergic reactions (possibly delayed).

Use during pregnancy or breastfeeding.

Use during pregnancy or breastfeeding is contraindicated, since sweet flag (Acorus calamus), an ingredient of the medicinal product, increases estrogen levels, thereby disrupting hormonal balance. If it is necessary to use the medicinal product, breastfeeding should be discontinued.

Ability to affect reaction rate when driving or operating machinery.

Does not affect the ability to drive a vehicle or operate complex machinery.

Dosage and Administration.

Administer orally. Adults and children aged 12 years and older: take 2 teaspoons (10 ml) of syrup 3–4 times daily; children aged 7 to 11 years: 1 teaspoon (5 ml) of syrup 4 times daily; children aged 3 to 6 years: 1 teaspoon (5 ml) of syrup 3 times daily; children aged 1 to 2 years: ½ teaspoon (2.5 ml) 3–4 times daily.

Duration of treatment: 3 to 7 days.

Children.

Do not administer to children under 1 year of age.

Overdose.

Overdose or prolonged use (more than 2 months) may cause disturbances in water-electrolyte balance, potentially leading to hypokalemic myopathy and myoglobinuria. Exacerbation of adverse effects is possible.

Adverse Reactions.

Weakness, increased arterial pressure, hypokalemia, allergic reactions (including rash, skin hyperemia, annular erythema, pruritus, urticaria, angioneurotic edema); increased salivation, irritation of gastric mucosa may occur during the use of the medicinal product.

If any adverse reactions occur, discontinue use of the medicinal product and consult a physician.

Reporting of suspected adverse reactions.

Reporting of suspected adverse reactions after registration of the medicinal product is an important procedure. It allows continuous monitoring of the benefit-risk balance of the medicinal product. Healthcare professionals are required to report any suspected adverse reactions through the national pharmacovigilance system.

Shelf life. 3 years.

Storage conditions.

Store in the original packaging at a temperature not exceeding 25 ºC.

Keep out of reach of children.

Packaging.

Syrup 90 ml, 120 ml, or 150 ml in a bottle No. 1, in a cardboard box.

Availability.

Over-the-counter.

Manufacturer.

Herbion Pakistan Private Limited, Pakistan / Herbion Pakistan Private Limited, Pakistan.

Manufacturer's address and place of business.

Plot №30 sector 28, Korangi Industrial Area, Karachi, Pakistan /
Plot №30 sector 28, Korangi, Industrial Area, Karachi, Pakistan.