Lespenefril-lubnifarm
Ukraine
Table of Contents
INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT LESPENEFRIL-LUBNYFARM (LESPENEFRIL-Lubnypharm)
Composition:
Active substance: extract of the shoots of Lespedeza bicolor (Cormus Lespedeza bicolor Turcz.) (1 : 4–5);
1 ml of solution contains extract of the shoots of Lespedeza bicolor (Cormus Lespedeza bicolor Turcz.) (1 : 4–5) — 0.9 ml (extractant — ethanol 70% v/v);
Excipients: purified water, anise oil.
Pharmaceutical form. Oral solution.
Main physicochemical properties: liquid, light brown to dark brown in color, with a characteristic odor. The presence of a sediment is permissible.
Pharmacotherapeutic group.
Agents used in urology. ATC code G04BX.
Pharmacological properties.
Pharmacodynamics.
The complex of biologically active substances contained in the medicinal product promotes increased renal filtration, reduces azotemia, accelerates the excretion of nitrogenous waste products with urine, increases diuresis, and enhances the excretion of sodium and, to a lesser extent, potassium.
Clinical characteristics.
Indications.
The medicinal product is intended for use in adults as a hypoazotemic and diuretic agent for symptomatic therapy in chronic renal failure.
Contraindications.
Individual hypersensitivity to the components of the medicinal product, pregnancy, breastfeeding, liver diseases, alcoholism, epilepsy, cranial trauma, brain disorders. Pediatric use under 18 years of age.
Special precautions.
When using the medicinal product, the physician's recommendations should be strictly followed.
Interaction with other medicinal products and other types of interactions.
Due to the presence of ethanol in the medicinal product, it should not be used concomitantly with disulfiram, sedatives, non-selective monoamine oxidase inhibitors, insulin, metformin, or sulfonylureas.
When prescribing multiple medicinal products simultaneously, the presence of ethanol in the formulation must be taken into account, as it may alter or potentiate the effects of other medicinal products.
Special precautions for use.
In case of developing hyponatremia, it should be corrected by administration of preparations containing sodium ions.
The medicinal product contains no less than 40% ethanol. The ethanol content in the maximum single dose of the medicinal product is no less than 4.7 g, and in the maximum daily dose—no less than 18.8 g.
Use during pregnancy or breastfeeding.
Lеспенефрил-Лубнифарм is contraindicated during pregnancy or breastfeeding.
Ability to influence reaction rate when driving or operating machinery.
Due to the presence of ethanol in the medicinal product, a reduction in psychomotor reactions is possible; this should be taken into account when driving vehicles or operating machinery.
Method of Administration and Dosage.
Lespenefril-Lubnifarm is taken orally, 5–15 ml (1 teaspoon — 1 tablespoon) 3–4 times daily. Dilution of the medicinal agent with water prior to administration is permitted.
Treatment duration: 3–4 weeks.
Repeating the treatment course is possible after 2–3 weeks only upon consultation with a physician.
Children.
The medicinal product is not intended for use in pediatric patients.
Overdose.
Symptoms of overdose are related to the presence of ethanol in the medicinal product.
Side effects.
Allergic reactions are possible. Rarely, the medicinal product may cause hyponatremia, which can be compensated by administration of sodium-containing preparations.
Shelf life.
3 years.
Storage conditions.
Store in the original packaging at a temperature not exceeding 25 °C.
Keep out of reach of children.
Packaging.
100 ml in a bottle, in a cardboard box.
Supply category.
Over-the-counter (without prescription).
Manufacturer.
JSC "Lubnipharm".
Manufacturer's address and place of business.
16, Barvinkova St., Lubny, Poltava region, 37500, Ukraine.