Frangula bark

INSTRUCTION FOR MEDICAL USE OF THE MEDICINAL PRODUCT FRANGULA BARK (FRANGULAECORTEX)

Composition:

Active substance: Frangula bark (Frangulaecortex).

1 pack contains Frangula bark (Frangulaecortex) – 75 g;
1 pack contains Frangula bark (Frangulaecortex) – 100 g;
1 filter bag contains Frangula bark (Frangulaecortex) – 2.5 g.

Pharmaceutical form. Bark.

Main physico-chemical characteristics: powdered raw material: fragments of bark of various shapes. The color of the bark on the outer side is grayish-brown or dark brown,
on the inner side – orange-brown, reddish-brown or dark red;

coarse powder: fragments of bark of various shapes, grayish-brown, dark brown, orange-brown, reddish-brown, or dark red in color.

Pharmacotherapeutic group. Contact laxatives. ATC code A06AB.

Pharmacological properties.

Pharmacodynamics.

The biologically active substances of the drug exert a mild laxative effect, the mechanism of which consists in enhancing the peristalsis of the large intestine, without irritating the mucous membrane and without affecting the small intestine. The laxative effect occurs 8–12 hours after administration.

Clinical characteristics.

Indications. Intestinal atony, habitual constipation.

Contraindications. Hypersensitivity to the biologically active substances of the drug. Neurogenic and endocrine constipation, spastic constipation, intestinal obstruction, gastrointestinal bleeding, acute abdomen syndrome, appendicitis, acute gastroenterocolitis, other inflammatory conditions within the abdominal cavity, acute infectious diseases.

Special precautions. Prolonged use of the drug leads to habituation and weakening or absence of laxative effect. To prevent habituation, it is advisable to alternate with other laxatives.

Interaction with other medicinal products and other types of interactions. Unknown.

Special precautions.

Use during pregnancy or breastfeeding. Contraindicated.

Ability to affect reaction speed when driving or operating machinery. Does not affect.

Method of Administration and Dosage.

Place 1 tablespoon of the bark into an enameled container, pour 200 mL of hot boiled water, cover, and steep in a water bath for 30 minutes. Allow to cool at room temperature for 10 minutes, then strain and squeeze the residue into the strained decoction. Adjust the volume of the decoction to 200 mL with boiled water. Administer warm: adults – ½ cup at bedtime; children aged 12 years and older – ¼ to ⅓ cup at bedtime. Shake the decoction before use.

Place 2 filter packets into a glass or enameled container, pour 100 mL of boiling water, cover, and let steep for 15–20 minutes. Administer warm: adults – 100 mL at bedtime; children aged 12 years and older – ¼ to ⅓ cup (50–60 mL) at bedtime.

The prepared aqueous extract should be stored at 8–15 °C for no more than 2 days.

The duration of treatment is determined individually by a physician.

Children. The use of the drug is recommended for children aged 12 years and older.

Overdose. In case of overdose, colicky abdominal pain, tenesmus, and discomfort may occur. If these symptoms appear, discontinue the drug. Treatment is symptomatic.

Side effects.

With prolonged use, the following may develop: diarrhea with metabolic disturbances, dehydration, reduced intestinal enzyme function, colon atony, colicky abdominal pain, allergic reactions.

Shelf life. 5 years.

Do not use after the expiry date stated on the packaging.

Storage conditions. Store in the original packaging at a temperature not exceeding 30 °C,
in a place inaccessible to children.

Packaging. 75 g or 100 g in packs with an inner pouch; 2.5 g in tea bags, packaged in sets of 20.

Dispensing category. Over-the-counter.

Manufacturer. JSC "Liktravy".

Manufacturer's location and address of business activity.
21, Kyivske Shose, Zhytomyr, 10001, Zhytomyr region, Ukraine.