Aloe extract liquid-darnitsa

INSTRUCTIONS FOR MEDICAL USE OF THE MEDICINAL PRODUCT Aloe extract liquid-Darnitsa (Aloe extract liquid-Darnitsa)

Composition:

Active substance: aloes extractum siccum;

1 ml of extract contains 2.25 mg of dried aloe extract (aloes extractum siccum), calculated as 100% content of calcium and magnesium salts of organic acids in the dry matter;

Excipients: sodium chloride, water for injections.

Pharmaceutical form. Liquid extract for injection.

Main physicochemical properties: a liquid ranging from light yellow to brownish-yellow in color, with a weak specific odor. The presence of a suspension is permissible in the preparation, which settles as a sediment upon storage, and forms a uniform suspension when the ampoules are shaken.

Pharmacotherapeutic group. Agents affecting the digestive system and metabolic processes. ATC code A16AX.

Pharmacological properties.

Pharmacodynamics.

Biogenic stimulant. Exerts adaptogenic and general tonic effects. Improves cellular metabolism, tissue trophism and regeneration, enhances general non-specific resistance of the organism and increases mucosal resistance to damaging agents. Stimulates protective functions of granulocytes, improves appetite. Increases energy reserves in spermatozoa and enhances their motility.

Pharmacokinetics.

Not studied.

Clinical characteristics.

Indications.

Progressive myopia, myopic chorioretinitis, blepharitis, conjunctivitis, keratitis, iritis, opacities of the vitreous body, as well as peptic ulcer disease of the stomach and duodenum (as part of complex therapy).

Contraindications.

Hypersensitivity to the drug. Severe cardiovascular diseases, arterial hypertension, acute gastrointestinal disorders (including diarrhea), intestinal obstruction, Crohn's disease, ulcerative colitis, appendicitis, abdominal pain of unknown origin, hemorrhoids, hepatic/renal dysfunction, complicated forms of nephrosis-nephritis, diffuse glomerulonephritis, cystitis, metrorrhagia, hemoptysis, cholelithiasis.

Interaction with other medicinal products and other forms of interaction.

Enhances the effect of agents stimulating hematopoiesis and iron-containing preparations. When used concomitantly with aloe extract and thiazide diuretics, loop diuretics, licorice preparations, or corticosteroids, the risk of developing potassium deficiency increases.

Special precautions for use

To prevent pain, 0.5 mL of 2% novocaine may be administered subcutaneously at the intended injection site prior to injection.

Use during pregnancy or breastfeeding

The medicinal product should not be used, as its mechanism of action (as a biogenic stimulator) has not been sufficiently studied.

Ability to influence the speed of reactions when driving or operating machinery

Not studied.

Method of Administration and Dosage.

If sediment is present, shake the ampoule before opening until a uniform suspension is formed.

Administer aloe extract subcutaneously daily: for adults – 1 mL (maximum daily dose – 3–4 mL); for children aged 3 to 5 years – 0.2–0.3 mL, for children aged 5 years and older – 0.5 mL. Treatment course consists of 30–50 injections. Repeat courses should be performed after an interval of 2 or 3 months.

Children

Use in children aged 3 years and older.

Overdose.

No cases of overdose have been reported. Possible intensification of adverse reactions.

Side effects.

Gastrointestinal disorders: tingling sensation, dyspepsia, abdominal pain.

Cardiovascular system disorders: increased blood pressure.

Immune system disorders: allergic reactions including: hyperemia, itching, rash, urticaria.

General disorders and administration site conditions: dizziness, sensation of blood rush to the pelvic organs, increased menstrual bleeding, burning sensation, hyperthermia, injection site reactions including hyperemia and itching.

Shelf life. 3 years.

Storage conditions.

Store in a place inaccessible to children, in the original packaging, at a temperature not exceeding 25 °C. Do not freeze.

Incompatibility.

The medicinal product must not be mixed with other medicinal products.

Packaging.

1 ml in an ampoule; 5 ampoules in a blister pack; 2 blister packs in a carton.

Prescription status. Prescription only.

Manufacturer. JSC "Pharmaceutical company "Darnytsia".

Manufacturer's address and place of business.

13, Borispilska Street, Kyiv, 02093, Ukraine.