to the nurse
to the nurse

What is
What is

("cytomegalovirus").

or or
or

to the nurse
or
or
"Other PREVYMIS"
of the other

the list
' "
"

used for the treatment of HIV

Breastfeeding the intake
" "
'
until the effect does not
" "

Body weight	Daily oral dose of PREVYMIS	Number of PREVYMIS tablets once daily
30 kg and above	480 mg	One 480 mg tablet or Two 240 mg tablets
15 kg to less than 30 kg	240 mg	One 240 mg tablet
Body weight	Daily oral dose of PREVYMIS	Number of PREVYMIS tablets once daily
30 kg and above	240 mg	One 240 mg tablet
15 kg to less than 30 kg	120 mg	See the package leaflet of PREVYMIS granules in sachets

a little water
at the scheduled time
the administration the administration

on the use
to the nurse.

to the nurse
reported in the '
to the latest
'
'
the environment.
"lactose" "PREVYMIS sodium".
of the ASP
("tablet")
"591" on the other.
("tablet")
"595" on the other.

of the marketing authorization to the placing
of the marketing authorization to the placing
България
Merck Sharp & Dohme Bulgaria EOOD
Tel.: +359 2 819 3737
Česká republika
Ελλάδα
A.F.E.E.
Tel
á
Κύπρος
Tel.: 800 00 673 (+357 22866700)
of the Agency

to the nurse.
to the nurse.

What is
What is

("cytomegalovirus").

or or
or

to the nurse
or
or
"Other PREVYMIS")
of the other

the list
").
' "
"

for the treatment of HIV

Breastfeeding the administration
'
until the
ll'1.15'
'

Body weight	Daily intravenous dose without cyclosporine	Daily intravenous dose with cyclosporine
30 kg and above	480 mg	240 mg
Body weight	Daily intravenous dose without or with cyclosporine
from 15 kg to less than 30 kg	120 mg
from 7.5 kg to less than 15 kg	60 mg
from 5 kg to less than 7.5 kg	40 mg

If you miss the appointment for administration of

the appointment

on use
to the nurse.

to the nurse.
brought in the '
at the last
'
'
'
'
'
the environment.
" "
"PREVYMIS".
of the appearance
of the marketing authorization
of the marketing authorization
България
Merck Sharp & Dohme Bulgaria Ltd
Tel.: +359 2 819 3737
Česká republika
Ελλάδα
A.F.E.E.
Tel
á
Κύπρος
Tel.: 800 00 673 (+357
of the Agency
the use
of the use

Intravenous dose	Volume of 20 mg/mL PREVYMIS concentrate for solution for infusion	Final infusion volume	Final letermovir concentration
120 mg	6 mL of 20 mg/mL	75 mL	1.6 mg/mL
60 mg	3 mL of 20 mg/mL	50 mL	1.2 mg/mL
Intravenous dose	Dilution volume of PREVYMIS 2 mg/mL (1:10)*	Final infusion volume	Final letermovir concentration
40 mg	20 mL of 2 mg/mL	20 mL	2 mg/mL
* To prepare the PREVYMIS 2 mg/mL dilution, add 5 mL of PREVYMIS 20 mg/mL concentrate for solution for infusion from the vial to 45 mL of diluent (sodium chloride 9 mg/mL (0.9%) or 5% dextrose) and gently mix.

inside
the entire
•
•
•
•
•
•
•
•
•
•
•
•
•
•
to the nurse.
to the nurse.

What is
What is

("cytomegalovirus").

or or
or

to the nurse
or
or
"Other PREVYMIS"
of the other

the list
' "
"

for the treatment of HIV

Breastfeeding the intake
4 "Possible side effects" below). Some patients have
'
until the effect does not
"
"

Body weight	Daily oral dose of PREVYMIS	Number of PREVYMIS sachets once daily
30 kg and above	480 mg	Four 120 mg sachets
15 kg to less than 30 kg	240 mg	Two 120 mg sachets
7.5 kg to less than 15 kg	120 mg	One 120 mg sachet
5 kg to less than 7.5 kg	80 mg	Four 20 mg sachets
Body weight	Daily oral dose of PREVYMIS	Number of PREVYMIS sachets once daily
30 kg and above	240 mg	Two 120 mg sachets
Body weight	Daily oral dose of PREVYMIS	Number of PREVYMIS sachets once daily
15 kg to less than 30 kg	120 mg	One 120 mg sachet
7.5 kg to less than 15 kg	60 mg	Three 20 mg sachets
5 kg to less than 7.5 kg	40 mg	Two 20 mg sachets

use '
at the time of
'
taking taking

on use
to the nurse.

to the nurse
in the '
in the last
in water
the environment.
"PREVYMIS lactose" "PREVYMIS sodium".
of the appearance

of the authorization to placing on the market

of the authorization to placing on the market
България
Merck Sharp & Dohme Bulgaria EOOD
Tel.: +359 2 819 3737
Česká republika
Ελλάδα
A.F.E.E.
Tel
á
Κύπρος
Tel.: 800 00 673 (+357 22866700)
of the Agency